Results 241 to 250 of about 24,883,480 (353)

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Obesity as a Risk Factor for Autoimmune Diseases: A Systematic Review and Meta-Analysis. [PDF]

Obesity (Silver Spring)
Spatocco I, Mele G, De Rosa G, Fusco C, Ruggiero K, Pellegrini V, Carreras F, La Grotta R, Ceriello A, Procaccini C, Matarese G, Prattichizzo F, de Candia P.   +12 more
europepmc   +1 more source

Obesity as an Independent Risk Factor for Cardiovascular Disease: A 26‐year Follow‐up of Participants in the Framingham Heart Study

Circulation, 1983
Helen B. Hubert, M. Feinleib, W. Castelli   +2 more
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Preterm Birth as a Risk Factor for Cerebral Palsy in Children: A Systematic Review and Meta-Analysis. [PDF]

Neurol Res Int
Tegegne KT, Wudu TK, Abebe MT, Tegegne ET, Tessema MK.   +4 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Hip osteoarthritis is not a risk factor for immune checkpoint inhibitor-induced inflammatory arthritis. [PDF]

J Rheumatol
Fitzpatrick R, Demehri S, Murray J, Brahmer JR, Ghotbi E, Barasa D, Bingham CO, Shah AA, Cappelli LC.   +8 more
europepmc   +1 more source

Sensitivity and Uncertainty Analyses for Burden of Disease and Risk Factor Estimates

, 2006
C. Mathers, Joshua A. Salomon, M. Ezzati, Stephen Begg, S. Hoorn, Alan D. Lopez   +5 more
semanticscholar   +1 more source

Ageing as a Risk Factor for Disease

Current Biology, 2012
T. Niccoli, L. Partridge
semanticscholar   +1 more source