Results 111 to 120 of about 26,899,739 (354)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Behavior Risk Factors and Lipid Profiles of Diabetes Mellitus with Hypertension Among Adult Population in Indonesia [PDF]

, 2016
Background: Diabetes mellitus (DM) with hypertension increases risk of disability and premature death. Data on DM with hypertension is limited to hospital based data, while population-based data is important to provide problem magnitude in the population
Aryastami, N. K. (Ni), Delima, D. (Delima), Krishnan, A. (Anand), Kusumawardani, N. (Nunik), Pradono, J. (Julianty), Suhardi, S. (Suhardi)   +5 more
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Assessment of intervention measures on trihalomethane in finished water by interrupted time series analysis

环境与职业医学
BackgroundThe Qingcaosha Reservoir is facing issues of algal blooms and eutrophication, and the resulting increase in the level of chlorination disinfection by-products in the water has been a major concern.
Yangyang REN, Hailei QIAN, Saifeng PEI, Xiaodong SUN, Zheng WU, Chen WU, Jingxian ZHOU, Aimin DU, Shaofeng SUI   +8 more
doaj   +1 more source

Epidemiology of sarcopenia: Prevalence, risk factors, and consequences.

Metabolism: Clinical and Experimental, 2023
S. Yuan, S. Larsson
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Research progress on ultra-processed foods consumption and its association with health

环境与职业医学
With the rapid progress of industrialization and commercialization, the sales and population intake of ultra-processed foods (UPFs) are constantly increasing globally. High UPFs intake is associated with various health issues.
Jiaqian ZHONG, Jiangyue YU, Zhengyuan WANG, Zhuo SUN, Jiajie ZANG   +4 more
doaj   +1 more source

An analysis of risk factors for carbapenem-resistant Enterobacteriaceae infection

, 2022
Yan Gao, Meilian Chen, Meng Cai, Kun Liu, Yimin Wang, Chengzheng Zhou, Zhigang Chang, Qi Zou, Shirou Xiao, Yang Cao, Weihua Wang, Zhuang Liu, Linfang Lv, Yajun Luo, Yinghong Wu   +14 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Genetic and non-genetic risk factors associated with atrial fibrillation

, 2022
Lindsay J. Young, Steve Antwi-Boasiako, Joel Ferrall, Loren E. Wold, Peter J. Mohler, Mona El Refaey   +5 more
openalex   +2 more sources