Results 101 to 110 of about 542,934 (330)

Evaluating covariance matrix forecasts in a value-at-risk framework [PDF]

open access: yes
Covariance matrix forecasts of financial asset returns are an important component of current practice in financial risk management. A wide variety of models, ranging from matrices of simple summary measures to covariance matrices implied from option ...
Christian A. Walter, Jose A. Lopez
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Revealing the structural microenvironment of high metastatic risk uveal melanomas following decellularisation

open access: yesScientific Reports
Uveal melanoma (UM) is a rare aggressive intraocular tumour that spreads most commonly to the liver in tumours with loss of one copy of chromosome 3 (HR-M3); current treatments for metastatic disease remain largely ineffective.
Karen Aughton   +3 more
doaj   +1 more source

Risk Assessment Model for Railway Track Maintenance Operations Based on Combined Weights and Nonlinear FCE

open access: yesApplied Sciences
Current risk assessment in railway track maintenance operations faces challenges (low spatiotemporal accuracy, limited adaptability to various scenarios, and tendency of linear fuzzy comprehensive evaluation (FCE) methods to underestimate high-risk ...
Rui Luan, Rengkui Liu
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

PyPortOptimization: A portfolio optimization pipeline leveraging multiple expected return methods, risk models, and post-optimization allocation techniques

open access: yesMethodsX
This paper presents PyPortOptimization, an automated portfolio optimization library that incorporates multiple methods for expected returns, risk return modeling, and portfolio optimization.
Rushikesh Nakhate   +2 more
doaj   +1 more source

Modification of the existing maximum residue level for fosetyl/phosphonic acid for potatoes and wheat

open access: yesEFSA Journal, 2019
In accordance with Article 6 of Regulation (EC) No 396/2005, the applicants Luxembourg Industries (Pamol) Ltd and De Sangosse SAS submitted a request to the competent national authority in France to modify the existing maximum residue level (MRL) for ...
European Food Safety Authority (EFSA)   +20 more
doaj   +1 more source

Some Improved Mixed Regression Estimators and their Comparison when Disturbance Terms follow Multivariate T-Distribution

open access: yesRatio Mathematica, 2017
The Mean square error matrices, bias vector and risk functions of proposed improved mixed regression estimators are obtained by employing the small disturbance approximation technique under the condition, when disturbance terms follows multivariate t ...
Manoj Kumar, Vikas Bist, Man Inder Kumar
doaj   +1 more source

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