Results 31 to 40 of about 542,934 (330)

Detection of a sparse submatrix of a high-dimensional noisy matrix [PDF]

, 2011
We observe a $N\times M$ matrix $Y_{ij}=s_{ij}+\xi_{ij}$ with $\xi_{ij}\sim {\mathcal {N}}(0,1)$ i.i.d. in $i,j$, and $s_{ij}\in \mathbb {R}$. We test the null hypothesis $s_{ij}=0$ for all $i,j$ against the alternative that there exists some submatrix ...
Butucea, Cristina, Ingster, Yuri I.
core   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Environmental risk assessment as a tool to identify potential hotspots of bacteria resistance worldwide

Emerging Contaminants, 2023
Pharmaceutical usage has led to the widespread detection of these compounds in aquatic ecosystems worldwide, raising concerns about the selective pressure they can exert on microbial communities.
Gabrielle Rabelo Quadra, Emília Marques Brovini, Renata de Oliveira Pereira, Yago Guida   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Credit Risk Assessment of Corporate Sector in Croatia [PDF]

Financial Theory and Practice, 2009
The main goal of this paper is modeling credit risk of non-financial businesses entities by assessing the rating migration probabilities and predicting the probability of default over one year horizon on the basis of corporate financial accounts.
Lana Ivicic, Saša Cerovac
doaj  

COLLAGEN MATRIX WITH INCREASED HEMOSTATIC PROPERTIES: COMPARATIVE ANALYSIS OF HEMOSTATIC EFFICACY [PDF]

Biotechnologia Acta
Aim. To develop collagen matrices with increased hemostatic properties and to evaluate their effectiveness in comparison with commercial products. Methods.
K.B. Baidakova, Y.P. Kucheryavyi, D.S. Korolova   +2 more
doaj   +1 more source

Modification of the existing maximum residue levels for fosetyl/phosphonic acid in various crops

EFSA Journal, 2020
In accordance with Article 6 of Regulation (EC) No 396/2005, the applicants BASF SE, Landwirtschaftliches Technologiezentrum Augustenberg and Tilco Biochemie GmbH submitted a request to the competent national authorities in Greece and Germany to modify ...
European Food Safety Authority (EFSA), Maria Anastassiadou, Giovanni Bernasconi, Alba Brancato, Luis Carrasco Cabrera, Luna Greco, Samira Jarrah, Aija Kazocina, Renata Leuschner, Jose Oriol Magrans, Ileana Miron, Stefanie Nave, Ragnor Pedersen, Hermine Reich, Alejandro Rojas, Angela Sacchi, Miguel Santos, Alois Stanek, Anne Theobald, Benedicte Vagenende, Alessia Verani   +20 more
doaj   +1 more source

A New Method to Estimate the Noise in Financial Correlation Matrices

, 2002
Financial correlation matrices measure the unsystematic correlations between stocks. Such information is important for risk management. The correlation matrices are known to be ``noise dressed''.
Bernd K lber, Bonanno G, Bouchaud J P, Burda Z, Dahlhaus R, Dyson F J, Eller R, Elton E J, Giada L, Gopikrishnan P, Gopikrishnan P, Haake F, Krengel U, Laloux L, Longerstaey J, Mantegna R N, Mantegna R N, Marsili M, Mehta M L, Noh J D, Paul W, Plerou V, Ross S, Sengupta A M, Thomas Guhr, Voit J, Wu F Y   +26 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source