Results 51 to 60 of about 542,934 (330)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Dynamic evolution of cross-correlations in the Chinese stock market
, 2013 We study the dynamic evolution of cross-correlations in the Chinese stock market mainly based on the random matrix theory (RMT). The correlation matrices constructed from the return series of 367 A-share stocks traded on the Shanghai Stock Exchange from ...
Ren, Fei, Zhou, Wei-Xing
core +3 more sources
Transition matrices in credit risk
, 2020 During the last decades, credit risk has been proved one of the greatest risks an institution is facing. This fact has forced banks and regulators all over the world to reassess the importance of credit risk and establish it as a core concept on their everyday activities.
openaire +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Julius-Kühn-Archiv, 2018 Residues of pesticides detected in pollen and nectar (bee relevant matrices) represent a realistic research approach to estimate pollinator exposure. Therefore, a robust and reliable method to sample and measure these residues is part of risk assessment ...
Knaebe, Silvio +3 more
doaj +1 more source
Optimising Investment Decisions in R&D Intensive Private Micro-Entities Using Game Theory [PDF]
Interdisciplinary Description of Complex Systems, 2023 In this article, three small private R&D intensive European entities have been used in a case study involving game theory combined with content analysis; in an attempt to identify an optimal investment strategy.
Andreas Georgiou
doaj
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Parisian ruin probability for Markov additive risk processes
Advances in Difference Equations, 2018 In this paper, we consider a spectrally negative Markov additive risk process. Using the theory of Jordan chain, a compact formula of Parisian ruin probability is given.
Xianghua Zhao, Hua Dong
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Zhejiang dianliIn recent years， several improper closing incidents of magnetically controlled switches have occurred in a certain region， significantly affecting the supply reliability of the power grids.
WANG Ziling +5 more
doaj +1 more source