Results 41 to 50 of about 3,369,849 (301)

Multivariate Shortfall Risk Allocation and Systemic Risk

open access: yes, 2017
The ongoing concern about systemic risk since the outburst of the global financial crisis has highlighted the need for risk measures at the level of sets of interconnected financial components, such as portfolios, institutions or members of clearing ...
Armenti, Yannick   +3 more
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Uncertainty in Pricing and Risk Measurement of Survivor Contracts

open access: yesRisks
As life expectancy increases, pension plans face growing longevity risk. Standardized longevity-linked securities such as survivor contracts allow pension plans to transfer this risk to capital markets.
Kenrick Raymond So   +4 more
doaj   +1 more source

Comparison of credit risk measurement in Central European banking [PDF]

open access: yes, 2018
This paper focuses on credit risk measurements in the financial institutions of Central Europe. The objective is to compare IRB approaches and a standardised approach to measuring credit risk in the Czech Republic, Germany and Poland.
Feng, Xiaoshan
core   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Duration and Risk of Unemployment in Argentina [PDF]

open access: yes, 2001
After a decade of structural reforms, unemployment rates have tripled in Argentina. This paper is concerned with the measurement of unemployment risk and its distribution.
Galiani, Sebastian, Hopenhayn, Hugo A.
core   +3 more sources

Volatility Spillover and Risk Measurement of Southeast Asian Financial Markets

open access: yesBAR: Brazilian Administration Review
Objective: this study aims to examine volatility transmission in ASEAN-5 financial markets during 2019–2023, covering pre-pandemic, pandemic, and post-pandemic phases, to analyze the impact of COVID-19 and other external factors, such as political crises
Fajrin Satria Dwi Kesumah, Rialdi Azhar
doaj   +1 more source

Assessing Financial Model Risk [PDF]

open access: yes, 2013
Model risk has a huge impact on any risk measurement procedure and its quantification is therefore a crucial step. In this paper, we introduce three quantitative measures of model risk when choosing a particular reference model within a given class: the ...
Barrieu, Pauline, Scandolo, Giacomo
core   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

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