Results 151 to 160 of about 3,028,894 (317)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Flood Risk Assessment Model Based on Cmip6 for the Northern Foothills of Qingling Mountain

open access: green
Adnan R. Ahmed   +6 more
openalex   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A risk model to predict atrial fibrillation in diabetes using machine learning: The ACCORD study. [PDF]

open access: yesAm Heart J Plus
Offerman EJ   +5 more
europepmc   +1 more source

DISTENDER indicators for Round 1 (only climate signal) and for: Air Quality and Emissions; Urban Heat Island; Health; Water; Energy; Agroforestry; Sectorial economy; Risk and Vulnerability. Case study: Guimaraes (Portugal). Global climate model: CAN-ESM5. Scenario: SSP126.

open access: green
DISTENDER   +6 more
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Peer Review #1 of "Predicting hedgehog mortality risks on British roads using habitat suitability modelling (v0.2)"

open access: gold, 2020
P. G. Wright   +99 more
openalex   +2 more sources

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