Results 171 to 180 of about 2,942,669 (315)

Bank Risk Management Based on Three Risk Measurement Models

, 2020
Jiadong Pu, Junjie Cheng
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

A novel manganese metabolism- and immune-related prognostic risk model for acute myeloid leukemia. [PDF]

Transl Cancer Res
Guo L, Cao Y, Gu WY, Lin Y.
europepmc   +1 more source

A Machine Learning Prediction Model to Identify Individuals at Risk of 5-Year Incident Stroke Based on Retinal Imaging [PDF]

Arun Govindaiah, Tasin Bhuiyan, R. Theodore Smith, Mandip S. Dhamoon, Alauddin Bhuiyan   +4 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Combining Biomarkers and Imaging for Short‐Term Assessment of Cardiovascular Disease Risk in Apparently Healthy Adults: A Paradigm‐Shifting Approach?

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Albert D. Osei, Michael J. Blaha
doaj   +1 more source

A Mendelian randomization-based risk model using aging-related genes for prognosis in lung adenocarcinoma. [PDF]

Discov Oncol
Feng S, Liu X, Yang H, Huang J, Wang Z, Li H, Cai J, Liu Z.   +7 more
europepmc   +1 more source

Optimizing Risk Control for Solar Farm Green Management Using DNI Estimation at the Edge Through a GLE-SVR Learning Model [PDF]

Mohammad Jafar Mokarram, Marzieh Mokarram, Mohamadreza Khosravi, Yukang Cui   +3 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Prognostic value of anoikis- and epithelial-mesenchymal transition-related genes and development of a prognostic risk model in thyroid cancer. [PDF]

Discov Oncol
Xiang KF, Wang L, Wu Y, Zhang D.
europepmc   +1 more source