Results 171 to 180 of about 3,028,894 (317)

METODE SIMULASI HISTORIS UNTUK PERHITUNGAN NILAI VALUE AT RISK PADA PORTOFOLIO DENGAN MODEL MARKOWITZ

, 2021
I Wayan Eka Sultra, Muhammad Rifai Katili, Muhammad Rezky Friesta Payu   +2 more
openalex   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Combining Biomarkers and Imaging for Short‐Term Assessment of Cardiovascular Disease Risk in Apparently Healthy Adults: A Paradigm‐Shifting Approach?

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Albert D. Osei, Michael J. Blaha
doaj   +1 more source

Association of PREVENT risk model with body fat distribution and subclinical left ventricular dysfunction. [PDF]

Am J Prev Cardiol
Hirose K, Nakanishi K, Daimon M, Sawada N, Konoma S, Kobayashi S, Seki H, Yoshida Y, Hirokawa M, Nakao T, Morita H, Di Tullio MR, Homma S, Kurano M, Takeda N.   +14 more
europepmc   +1 more source

Bio-economic modelling of decisions under yield and price risk for suckler cow farms

, 2012
Simon Briner, Robert Finger, Briner, Simon, Finger, Robert   +3 more
openalex   +2 more sources

An overview of measuring and modelling dose and risk from ionising radiation for medical exposures [PDF]

, 2014
Andrew Tootell, Katy Szczepura, Peter Hogg   +2 more
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A public health risk model using prior healthcare exposures identifies healthcare-associated pathogen carriage. [PDF]

Infect Control Hosp Epidemiol
Sansom SE, Shull T, Hayden MK, Schoeny M, Tang A, Vue M, Runez AT, Jovanov D, Trick WE, Lin MY.   +9 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Is the Parsimonious Eurolung risk model a good predictor for all populations? An external validation study. [PDF]

J Cardiothorac Surg
Leite F, Silva AM, Paupério G, Santos LL.   +3 more
europepmc   +1 more source