Results 61 to 70 of about 34,016,939 (394)
Prognostic Implication of Energy Metabolism-Related Gene Signatures in Lung Adenocarcinoma
BackgroundLung adenocarcinoma (LUAD) is the major non-small-cell lung cancer pathological subtype with poor prognosis worldwide. Herein, we aimed to build an energy metabolism-associated prognostic gene signature to predict patient survival.MethodsThe ...
Teng Mu, Haoran Li, Xiangnan Li
doaj +1 more source
Model Risk in Portfolio Optimization [PDF]
We consider a one-period portfolio optimization problem under model uncertainty. For this purpose, we introduce a measure of model risk. We derive analytical results for this measure of model risk in the mean-variance problem assuming we have observations drawn from a normal variance mixture model. This model allows for heavy tails, tail dependence and
David Stefanovits+2 more
openaire +5 more sources
Utility of the SENIORS elderly heart failure risk model applied to the RICA registry of acute heart failure [PDF]
Background: Heart failure (HF) is predominantly a disease of the elderly. Reliable risk stratification would help in the management of this population, but no model has been well evaluated in elderly HF patients in both acute and chronic settings and not
Bettencourt, Paulo+9 more
core +1 more source
Background: ith the ongoing development of targeted therapy, non-apoptotic cell death, including necroptosis, has become a popular topic in the field of prevention and treatment.
Chen Ji, Yue He, Yan Wang
doaj +1 more source
Action, Deontology, and Risk: Against the Multiplicative Model [PDF]
Deontological theories face difficulties in accounting for situations involving risk; the most natural ways of extending deontological principles to such situations have unpalatable consequences.
Tenenbaum, Sergio
core +1 more source
BackgroundAutophagy plays an important role in triple-negative breast cancer (TNBC). However, the prognostic value of autophagy-related genes (ARGs) in TNBC remains unknown. In this study, we established a survival model to evaluate the prognosis of TNBC
Cheng Yan+4 more
doaj +1 more source
Analyzing and Calibrating Risk Assessment by Software Developers [PDF]
In software project management, risk management is a critical factor. Project managers use existing lists of risk or perform brainstorming to identify the risks. However, it is not easy to perceive all the risks objectively. As a result, some risks are perceived based on subjective impression, which leads to risk biases.
arxiv
Incorporating Truncating Variants in PALB2, CHEK2 and ATM into the BOADICEA Breast Cancer Risk Model
Purpose:The proliferation of gene panel testing precipitates the need for a breast cancer (BC) risk model that incorporates the effects of mutations in several genes and family history (FH).
Andrew J. Lee+6 more
semanticscholar +1 more source
Biomarkers of leukemia risk: benzene as a model. [PDF]
Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
core +3 more sources
Estimating value at risk and conditional tail expectation for extreme and aggregate risks [PDF]
In this paper, we investigate risk measures such as value at risk (VaR) and the conditional tail expectation (CTE) of the extreme (maximum and minimum) and the aggregate (total) of two dependent risks. In finance, insurance and the other fields, when people invest their money in two or more dependent or independent markets, it is very important to know
arxiv