Results 71 to 80 of about 2,242,282 (346)

PrEP risk perception and adherence among men who have sex with men: a prospective cohort study based on growth mixture model

BMC Infectious Diseases, 2022
Background It can be considered that pre-exposure prophylaxis (PrEP) risk perception is the negative experiences or concerns about taking PrEP. The aim of this study is to explore the longitudinal trajectory of PrEP risk perception among men who have sex
Bing Lin, Jiaxiu Liu, Xiaoni Zhong
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Interpersonal and intrapersonal differences among adolescent nonsmokers, ex-smokers, and smokers [PDF]

, 2017
Background: A large body of research has traced tobacco dependence among adolescents to a series of intrapersonal and interpersonal factors. However, there are remaining questions regarding the differences on these factors related to tobacco use ...
Baiocco, Roberto, Dittrich, Marcella, Ioverno, Salvatore, Laghi, Fiorenzo, Odorifero, Carmen, Verrastro, Valeria   +5 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Household disposal of pharmaceuticals: attitudes and risk perception in a UK sample [PDF]

, 2022
Scott C. Watkins, Julie Barnett, Martyn Standage, Barbara Kasprzyk‐Hordern, Ruth Barden   +4 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Differentiating the effects of negative state on optimism and the implicit perception of everyday injury risk [PDF]

, 2012
To date no research has examined the effects of negative state on the perception of everyday injury risk. Instead, studies have focussed more broadly on the relationship between mood and self- reported optimism. The present study had two aims.
Garthwaite, J, Morgan, J
core  

BULGARIAN FARMER'S PERCEPTION TOWARDS RISK [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2023
The characteristics that influence farmer's behavior and attitude toward risk should be identified in order to explain inconsistencies between the farmer's perception of risk and the accurate measurement of the probability of the occurrence of a risk ...
Hristina HARIZANOVA-BARTOS, Zornitsa STOYANOVA   +1 more
doaj  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

General knowledge about climate change, factors influencing risk perception and willingness to insure [PDF]

In two empirical surveys in Germany the link between the information respondents have about climate change and their risk perception of the phenomenon was analysed.
Menny, Claas, Osberghaus, Daniel, Pohl, Max, Werner, Ute   +3 more
core