Results 51 to 60 of about 6,268,814 (252)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Profit allocation method of coalition including multi-energy based on Nash-Harsanyi game theory
Diance yu yibiaoEnergy resources belonging to independent owners under the background of multi-energy coalition participating in the market, thus ensuring the fairness of the profit allocation of each player becomes crucial.
LIU Zeyuan +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Frontiers in Psychology, 2017 Despite the fact that people make decisions for others as often as they make decisions for themselves, little is known about how decisions for others are different from those made for the self.
Xiangyi Zhang +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Preference elicitation and preference uncertainty: an application to noise valuation [PDF]
, 2011 The valuation of environmental impacts through Choice Experiments (CE) has been increasing applied in order to estimate the cost of environmental externalities.
Dave, Kaushali
core +4 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Self-Employment and Risk Preference. [PDF]
Business Performance; Risk Preference; Self ...
Michael Dietrich +3 more
core
Risk lovers, mixed risk loving and the preference to combine good with good
, 2019 This paper examines the concept of 'risk loving' (that is risk seeking, intemperance, edginess, etc.), which can be characterised by preferences over simple lotteries.
Mitra, S., Jokung, O.
core +4 more sources