Results 41 to 50 of about 54,392 (217)

Health Risk Map related to Particulate Matter Exposure in Chiang Mai, Thailand

open access: yesChemical Engineering Transactions, 2021
Ambient Particulate Matter; PM2.5, with an aerodynamic diameter smaller than or equal to 2.5 µm, has emerged as the most critical health hazard concerning air pollution.
Kannika Jarernwong   +2 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Physicochemical Properties of Chemical Pollutants Available in Food Contact Materials (FCM) [PDF]

open access: yesMATEC Web of Conferences, 2019
Health and welfare of population are priority reasons to study the toxic effects of chemical pollutants. These effects can directly produce deterioration of health or can cause less healthful environment toxicity and restricting food production. Thereby,
Farhat Joanna   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Multi-Factor Coupled Assessment of Seismic Disaster Risk for Buildings: A Case Study of Ankang City

open access: yesBuildings
This study presents a multi-factor coupled assessment of seismic disaster risk for approximately 635,000 individual building units in Ankang City, Shaanxi Province, China, utilizing a high-resolution dataset.
Dan Shao   +4 more
doaj   +1 more source

Employing Multi Attributes Decision Making Techniques for Rating the Supply Chain Risk Factors (Case Study: the field of information technology in small and medium enterprises) [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2011
Supply chain is a network of independent organizations that cooperate with each other, in order to control, manage and improve material and information flow from suppliers to final consumers to meet customer satisfaction.
Haidar Mirfakhroddini   +2 more
doaj  

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