Results 161 to 170 of about 351,543 (287)

Invasive Alien Species of European Union Concern: A Systematic Review of High-Priority Pathogens in 22 Species in a One Health Framework. [PDF]

Animals (Basel)
Spadotto L, Centelleghe C, Ceolotto L, Mazzariol S, Cavicchioli L.   +4 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Assessing Shifts in Research Priority Areas From the Neurological Community Before and After the COVID-19 Pandemic. [PDF]

Health Expect
Dempsey L, Cruickshank T, Turner M, Laws M, Bartlett D, Singer B, van der Groen O, Sim M, Stanley M.   +8 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Perinatal mental health research: priorities from a neurodiverse sample in the United Kingdom. [PDF]

Arch Womens Ment Health
Lautarescu A, Heraty S, Johnson C, Ruigrok A, Eaton E, Bazelmans T, Sigurdardottir J, Ratti V, Stone H, Anderson J, Javed A, Mahtani S, Lau-Zhu A, Smith DM.   +13 more
europepmc   +1 more source

Analysis of Risk Priority Number for Grid-connected Energy Storage System

Journal of the Korean Society of Safety, 2016
Doo-Hyun Kim, Sung-Chul Kim, Jeon-Su Park, Eun-Jin Kim, Eui-Sik Kim   +4 more
openaire   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Use of failure mode and effects analysis for risk analysis of investigational drug products management in clinical trials. [PDF]

Am J Health Syst Pharm
Zhang B, Song M, Wang Z, Zhou Y, Pang X.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A Risk-Based Isolation Strategy for MDR-Endemic Facilities with Limited Resources. [PDF]

Infect Dis Rep
Ture Z, Alp E.
europepmc   +1 more source