Results 151 to 160 of about 18,207,286 (255)

Downturn model risk: Another view of the global financial crisis

, 2010
Researchers and practitioners have spent ample resources modelling credit, explaining correlations between risk models as well as inputs and outputs.
Roesch, D, Scheule, H
core  

ReFraming The FaPMI (Families Where a Parent Has a Mental Illness) Program: Using a Participatory Action Research Approach to Create Change. [PDF]

Int J Ment Health Nurs
Allchin B, Morgan A, Clark C, Jewell H, Legge J, Schinas J, Mack H, McCall A, Cameron D, Chalmers A, Cosgriff C, Creswick A, Dickenson S, Forster I, Foster D, Fraser E, Harbor P, Hegarty M, Henley K, McCormack F, McGregor T, Nguyen AT, Rabbitt K, Sanders B, Sarikoudis V, Stead M, Stephenson N, Tesoriero L, Timmins G, Zinnack H.   +29 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Fatigue and Driving Safety in Early Parenthood: Developing Feasible Risk-Reduction Strategies Through Co-Design. [PDF]

Health Promot J Austr
Sprajcer M, Kovac K, Thomas MJW, Ferguson SA, Gupta CC, Bachmann A, Miller DJ, Thorne H, Bishop BC, Vincent GE.   +9 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Strengthening One Health: Global Applications of the Joint Risk Assessment Operational Tool. [PDF]

Pathogens
Prasarnphanich OO, Dorjee S, Ahmad R, Brown R, Calvin S, Do H, Hoejskov PS, Ismayilova G, Kato M, Kuriata O, Lopes JK, Mahrous H, Scheuermann L, Traore T, Vrbova L, Waddell JT, Wannous C, Wulandari EW, Gongal G, de la Rocque S.   +19 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Service delivery interventions for lipid testing and lipid-lowering therapy for primary and secondary prevention of cardiovascular disease in adults. [PDF]

Cochrane Database Syst Rev
Zorger AM, Muth A, Shokraee K, Olfati S, Monsef I, Franco JV, Skoetz N.   +6 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Cardiovascular risk estimation using the steno type 1 risk engine in Brazilian individuals with type 1 diabetes: a multicenter cross-sectional study. [PDF]

Clinics (Sao Paulo)
Gomes MB, Albuquerque FOB, Matheus A, Canani LH, Forti AC, Chaves RM, Pavin EJ, Junior RM, Dib SA, Felicio JS, Réa RR, Nery M, Negrato CA, Silva LC.   +13 more
europepmc   +1 more source