Results 201 to 210 of about 18,207,286 (255)

Risk management & insurance review: Tomo 25 Número 1 - 2022

, 2022
American Risk and Insurance Association
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Risk management & insurance review: Tomo 25 Número 2 - 2022

, 2022
American Risk and Insurance Association
core  

Primary Healthcare Professionals' Perspectives on Cardiovascular Risk Communication to Persons With Type 2 Diabetes: A Grounded Theory Study. [PDF]

Nurs Open
Stenlund AL, Hellström Ängerud K, Lilja M, Otten J, Jutterström L.   +4 more
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

An Expert-Derived Data-Driven Approach to Identifying Medicaid Children at Risk of Out-of-Home Placement: Development, Application, and Data-Sharing Considerations. [PDF]

Med Care
Hardy RY, Ciccone DP, Bailey E, Bozada S, Donnelly E, Tossone K, Chisolm DJ.   +6 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

A group-based hands-on seminar for teaching failure mode and effects analysis in CyberKnife stereotactic radiotherapy. [PDF]

J Appl Clin Med Phys
Okamoto H, Nishioka S, Kamomae T, Okawa K, Kikuchi S, Suzuki J.   +5 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

A study protocol for co-designing risk communication strategies for hepatitis C virus (HCV) testing among priority populations in Johannesburg district, Gauteng, South Africa. [PDF]

Discov Public Health
Chauke NP, Mashamba-Thompson T, Maluleke K.   +2 more
europepmc   +1 more source