Results 71 to 80 of about 6,437,662 (327)

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Microbial communities in biological denitrification system using methanol as carbon source for treatment of reverse osmosis concentrate from coking wastewater

open access: yesJournal of Water Reuse and Desalination, 2018
A biological denitrifying process using methanol as a carbon source was employed for the treatment of reverse osmosis concentrate (ROC) from coking wastewater in a sequencing batch reactor (SBR).
Enchao Li, Xuewen Jin, Shuguang Lu
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Optimization of low-carbon multi-energy systems with seasonal geothermal energy storage: The Anergy Grid of ETH Zurich

open access: yesEnergy Conversion and Management: X, 2020
We investigate the optimal operation of multi-energy systems deploying geothermal energy storage to deal with the seasonal variability of heating and cooling demands. We do this by developing an optimization model that improves on the state-of-the-art by
Paolo Gabrielli   +5 more
doaj  

A Comparative Frequency Analysis of Maximum Daily Rainfall for a SE Asian Region under Current and Future Climate Conditions

open access: yesAdvances in Meteorology, 2017
The impact of changing climate on the frequency of daily rainfall extremes in Jakarta, Indonesia, is analysed and quantified. The study used three different models to assess the changes in rainfall characteristics.
Velautham Daksiya   +2 more
doaj   +1 more source

On competing risk and degradation processes

open access: yes, 2006
Lehmann's ideas on concepts of dependence have had a profound effect on mathematical theory of reliability. The aim of this paper is two-fold. The first is to show how the notion of a ``hazard potential'' can provide an explanation for the cause of dependence between life-times.
openaire   +3 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Exogenous iron alters uptake and translocation of CuO nanoparticles in soil-rice system: A life cycle study

open access: yesEnvironment International, 2022
The abundant iron in farmland soil may affect the environmental fate of metal-based nanoparticles (MNPs). In this study, the effect of FeSO4 and nano-zero-valent iron (nZVI) as exogenous iron on the uptake and translocation of CuO nanoparticles (NPs) in ...
Qi Zhang   +6 more
doaj  

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