Results 221 to 230 of about 17,508,447 (350)

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Advances in Beyond Statin Lipid Therapies for ASCVD Risk Reduction. [PDF]

J Atheroscler Thromb
Shimabukuro M.
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Promoting risk reduction: increasing public health capacity to address dementia. [PDF]

Gerontologist
Roberts SS, Lewis M, Colcombe CW, Kline C, Donnelly JM, Denno B, Snyder HM, Baumgart M.   +7 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

All Hazards Great and Small: Applying Disaster Risk Reduction to Environmental Justice Communities in South Carolina. [PDF]

Geohealth
Kilpatrick DJ, Long KD, Muhammad O, Porter DE, Sandifer PA, Sprayberry K, Altman K, Briggs S, Brittain B, Button N, Cooper JA, Cothran J, Dewitt B, DiSalvo T, Fraser-Rahim H, Greene C, Harris G, Washok-Jones K, Kimble S, Koester M, Kulkarni N, Maybank H, McGirr M, Owoh J, Reese R, Schaafsma M, Day Taylor J, Kelsey H, Koppa N, Wilson D.   +29 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Cardiometabolic risk reduction with digital twinning in patients with type 2 diabetes. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Seyedi SA, González-Rivas JP, Mellacheruvu P, Mellacheruvu A, Aledavood SP, Esteghamati A, Mechanick JI.   +6 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Risk reduction behaviours following the detection of unexpected drugs through community drug checking: a cross-sectional study. [PDF]

Harm Reduct J
Tobias S, Grant C, Lysyshyn M, Roux P, Wood E, Kerr T, Ti L.   +6 more
europepmc   +1 more source