Results 161 to 170 of about 1,380,859 (329)

Effective Adaptation Options to Alleviate Nuisance Flooding in Coastal Megacities—Learning From Ho Chi Minh City, Vietnam

open access: yesEarth's Future
The economies and livelihoods of many coastal megacities are at serious risk from flooding, despite investments in flood defenses. For instance, in Ho Chi Minh City, the construction of a large‐scale ring‐dike has mitigated negative effects from storm ...
Leon Scheiber   +13 more
doaj   +1 more source

Crossroads at Mmamabula: Will the World Bank Choose the Clean Energy Path? [PDF]

open access: yes
At the recent UN climate change conference in Bali, UN Secretary General Ban Ki-moon called for a revolutionary change in the world’s energy mix to minimize the risk of catastrophic global heating.
David Wheeler
core   +1 more source

Forgotten Youth: Re-Engaging Students Through Dropout Recovery [PDF]

open access: yes, 2012
Each year, thousands of Massachusetts students drop out of school. The path forward for these students is difficult, and failing to fully educate the next generation of workers and leaders has substantial long-term consequences for our shared economic ...

core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Technology assessment between risk, uncertainty and ignorance [PDF]

open access: yes, 2012
The use of most if not all technologies is accompanied by negative side effects, While we may profit from today’s technologies, it is most often future generations who bear most risks.
Hillerbrand, Rafaela
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Breast and ovarian cancer risk reduction options for women with pathogenic variables in the brca1 and brca2 genes

open access: bronze, 2020
Sandro Melo   +4 more
openalex   +1 more source

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