Results 161 to 170 of about 9,368,536 (289)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Empirical insights into residual emissions in urban net-zero targets. [PDF]

Nat Clim Chang
Ulpiani G, Rodriguez Mendez Q, Todeschi V, Hernandez Moral G, Vetters N, Pittalis M, Fuss S, Gevers Deynoot C, Creutzig F.   +8 more
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Iatrogenic Metacarpal Shaft Fracture Following Distal Radius External Fixator Removal in Clinic. [PDF]

Case Rep Orthop
Scarano K, Smith V, Bair J.
europepmc   +1 more source

Chronic Disease Risk Reduction: 2018 Success Stories

, 2018
"Chronic diseases, such as heart disease, stroke, cancer, diabetes and arthritis, are the leading causes of death and disability in Kansas. Chronic diseases are preventable because most of the illness, disability and premature death related to these ...
Kansas. Department of Health and Environment.
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Navigating Therapeutic Frontiers: A Meta-review and Meta-analysis of COVID-19 Treatment Options. [PDF]

J Res Pharm Pract
Mousavi S, Ardekani MB, Feizi A.
europepmc   +1 more source

Prices and volumes of options: A simple theory of risk sharing when markets are incomplete [PDF]

We present a simple theory of business-cycle movements of option prices and volumes. This theory relies on time-varying heterogeneity between agents in their demand for insurance against aggregate risk.
Ragot, X., Le Grand, F.
core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Rescue transseptal percutaneous mitral balloon valvuloplasty for early bioprosthetic mitral valve thrombosis during VA-ECMO support: a case report. [PDF]

Eur Heart J Case Rep
Feu Masdemont A, Mayans JP, Úbeda TT, Monastyrski AV, Martín EAA.   +4 more
europepmc   +1 more source