Results 31 to 40 of about 11,478,693 (361)

Venous Thromboembolism Risk Score and Pregnancy

Frontiers in Cardiovascular Medicine, 2022
Venous thromboembolism (VTE) is a major contributor to maternal morbidity and mortality worldwide. Pregnancy is associated with the development of a baseline hypercoagulable state.
Tiphaine Raia-Barjat, Tiphaine Raia-Barjat, Osasere Edebiri, Céline Chauleur, Céline Chauleur   +4 more
doaj   +1 more source

Development of a Novel Sphingolipid Signaling Pathway-Related Risk Assessment Model to Predict Prognosis in Kidney Renal Clear Cell Carcinoma

Frontiers in Cell and Developmental Biology, 2022
This study aimed to explore underlying mechanisms by which sphingolipid-related genes play a role in kidney renal clear cell carcinoma (KIRC) and construct a new prognosis-related risk model.
Yonghao Sun, Yingkun Xu, Xiangyu Che, Guangzhen Wu   +3 more
doaj   +1 more source

Predictive Ability of a Clinical-Genetic Risk Score for Venous Thromboembolism in Northern and Southern European Populations

TH Open, 2021
Venous thromboembolism (VTE) is a complex, multifactorial problem, the development of which depends on a combination of genetic and acqfiguired risk factors.
Eduardo Salas, Maria Farm, Sara Pich, Liselotte Onelöv, Kevin Guillen, Israel Ortega, Jovan P. Antovic, Jose Manuel Soria   +7 more
doaj   +1 more source

The Identifying Depression Early in Adolescence Risk Stratified Cohort (IDEA-RiSCo): Rationale, Methods, and Baseline Characteristics

Frontiers in Psychiatry, 2021
Background: The characterization of adolescents at high risk for developing depression has traditionally relied on the presence or absence of single risk factors.
Christian Kieling, Christian Kieling, Claudia Buchweitz, Claudia Buchweitz, Arthur Caye, Arthur Caye, Pedro Manfro, Pedro Manfro, Rivka Pereira, Rivka Pereira, Anna Viduani, Anna Viduani, Maurício Anés, Lucas Battel, Lucas Battel, Silvia Benetti, Silvia Benetti, Helen L. Fisher, Helen L. Fisher, Rakesh Karmacharya, Brandon A. Kohrt, Thais Martini, Thais Martini, Sandra Petresco, Sandra Petresco, Jader Piccin, Jader Piccin, Thiago Rocha, Thiago Rocha, Luis Augusto Rohde, Luis Augusto Rohde, Fernanda Rohrsetzer, Fernanda Rohrsetzer, Laila Souza, Laila Souza, Bruna Velazquez, Bruna Velazquez, Annabel Walsh, Leehyun Yoon, Zuzanna Zajkowska, Valentina Zonca, Valentina Zonca, Johnna R. Swartz, Valeria Mondelli, Valeria Mondelli   +44 more
doaj   +1 more source

Polygenic risk scores

Seminars in Arthritis and Rheumatism
Polygenic risk scores (PRS) estimate an individual's genetic risk for a disease or trait compared to a matched population. For many rheumatic diseases PRS have been developed that have discriminatory capacity better than some widely used biomarkers, and in some cases are the most discriminatory tests available.
Brian T. Palmisano, Joshua W. Knowles
  +6 more sources

Construction of Prognostic Risk Prediction Model of Oral Squamous Cell Carcinoma Based on Nine Survival-Associated Metabolic Genes

Frontiers in Physiology, 2021
The aim was to investigate the independent prognostic factors and construct a prognostic risk prediction model to facilitate the formulation of oral squamous cell carcinoma (OSCC) clinical treatment plan.
Zhen-Dong Huang, Zhen-Dong Huang, Yang-Yang Yao, Ting-Yu Chen, Yi-Fan Zhao, Chao Zhang, Yu-Ming Niu, Yu-Ming Niu   +7 more
doaj   +1 more source

Analysis of polygenic risk score usage and performance in diverse human populations

Nature Communications, 2019
A historical tendency to use European ancestry samples hinders medical genetics research, including the use of polygenic scores, which are individual-level metrics of genetic risk.
L. Duncan, Hanyang Shen, B. Gelaye, J. Meijsen, K. Ressler, M. Feldman, Roseann E. Peterson, B. Domingue   +7 more
semanticscholar   +1 more source

Clinical Utility of Lipoprotein(a) and LPA Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular Disease

JAMA cardiology, 2020
Key Points Question Does measurement of lipoprotein(a) and/or LPA genetic risk score (GRS) have clinical utility in risk prediction of incident atherosclerotic cardiovascular disease (ASCVD)?
M. Trinder, M. Uddin, Phoebe Finneran, Krishna G. Aragam, P. Natarajan   +4 more
semanticscholar   +1 more source

Comparison of two different methods for cardiovascular risk assessment: Framingham risk score and SCORE system [PDF]

Journal of Medical Biochemistry, 2007
Numerous studies have shown that the major risk factors for coronary heart disease (cigarette smoking, hypertension, elevated serum total cholesterol and low-density lipoprotein cholesterol - LDL, low serum high-density lipoprotein cholesterol - HDL ...
Jovičić Snežana, Ignjatović Svetlana, Majkić-Singh Nada   +2 more
doaj  

Effects of Inflammation on the Immune Microenvironment in Gastric Cancer

Frontiers in Oncology, 2021
BackgroundChronic inflammation and immune cell dysfunction in the tumor microenvironment are key factors in the development and progression of gastric tumors.
Weidan Zhao, Mingqing Liu, Mingyue Zhang, Yachen Wang, Yingli Zhang, Shiji Wang, Nan Zhang   +6 more
doaj   +1 more source