Results 91 to 100 of about 7,108,051 (302)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Implementing Risk Adjusted Capitation Payments with Health Care Reforms in Hung
Competitio, 2008 Since the late nineties Hungarian governments have been considering the introduction of new health care arrangements by establishing organizations with devolved responsibilities for the management of health care.
Balazs Nagy, Agnes Brandtmüller
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Risk Sharing, Commitment and Information: An experimental analysis [PDF]
This paper describes and analyzes the results of a unique field experiment especially designed to test the effects of the level of commitment and information available to individuals when sharing risk.
Garance Genicot, Abigail Barr
core
West African Monetary Integration and Interstates Risk-Sharing [PDF]
There are continuing efforts at the monetary integration and unionization in West Africa. Several academics argue that a monetary union among West African states would be costly because of the magnitude of asymmetric shocks.
Sampawende Jules TAPSOBA
core +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Government Size and International Consumption Risk Sharing [PDF]
We investigate the influence of government size on the exposure of consumption growth to country-specific fluctuations in output growth using a sample of OECD countries.
Johann Scharler, Markus Leibrecht
core
Axiomatic characterizations of certain simple risk-sharing rules
Risk SciencesIn this paper, we present axiomatic characterizations of certain simple risk-sharing (RS) rules, such as uniform, mean-proportional and covariance-based linear RS rules.
Jan Dhaene +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Intergenerational Risk-Sharing and Risk-Taking of a Pension Fund [PDF]
By using their financial reserves efficiently, pension funds can smooth shocks on asset returns, and can thus facilitate intergenerational risk-sharing.
Christian Gollier
core