Results 91 to 100 of about 7,455,679 (304)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Channels of risk-sharing among Canadian provinces: 1961--2006 [PDF]

open access: yes
This paper incorporates recent developments in the literature to quantify the amount of interprovincial risk-sharing in Canada. We find that 29% of shocks to gross provincial product are smoothed by capital markets, 27% are smoothed by the federal tax ...
Balli, Faruk   +2 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Self-Production, Friction, and Risk Sharing against Disasters: Evidence from a developing country [PDF]

open access: yes
This paper uses a unique household data set collected in Vietnam to empirically test the necessary conditions for an extended version of the consumption risk-sharing hypothesis.
NAKATA Hiroyuki   +2 more
core  

Implementing Risk Adjusted Capitation Payments with Health Care Reforms in Hung

open access: yesCompetitio, 2008
Since the late nineties Hungarian governments have been considering the introduction of new health care arrangements by establishing organizations with devolved responsibilities for the management of health care.
Balazs Nagy, Agnes Brandtmüller
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Intergenerational Risk-Sharing and Risk-Taking of a Pension Fund [PDF]

open access: yes
By using their financial reserves efficiently, pension funds can smooth shocks on asset returns, and can thus facilitate intergenerational risk-sharing.
Christian Gollier
core  

Risk Sharing and Shock Propagation in Global Value Chains: A Structural Stress Test in a Multilayer Trade Finance Network

open access: yesRisks
Global value chains can diversify risk, but they can also transmit production disruptions and financial losses across interconnected economies. This study examines whether trade–finance coupling amplifies systemic loss relative to a trade-only benchmark,
Georgios Angelidis
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Axiomatic characterizations of certain simple risk-sharing rules

open access: yesRisk Sciences
In this paper, we present axiomatic characterizations of certain simple risk-sharing (RS) rules, such as uniform, mean-proportional and covariance-based linear RS rules.
Jan Dhaene   +2 more
doaj   +1 more source

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