Results 321 to 330 of about 7,544,041 (411)

PRMT1‐Mediated SWI/SNF Complex Recruitment via SMARCC1 Drives IGF2BP2 Transcription to Enhance Carboplatin Resistance in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu   +22 more
wiley   +1 more source

Risk stratification in neuroblastoma patients through machine learning in the multicenter PRIMAGE cohort. [PDF]

open access: yesFront Oncol
Lozano-Montoya J   +13 more
europepmc   +1 more source

A Novel Dual‐Network Approach for Real‐Time Liveweight Estimation in Precision Livestock Management

open access: yesAdvanced Science, EarlyView.
A novel dual‐network framework is proposed for real‐time, non‐contact liveweight estimation of pigs. By extracting contour information instead of segmented images, the method achieves high accuracy (R2 = 0.993) and an exceptional speed of 1131.6 FPS. This approach enhances automation in livestock farming, providing a scalable and efficient solution for
Ximing Dong   +6 more
wiley   +1 more source

Risk Stratification and Treatment Selection in Patients With Asymptomatic Abdominal Aortic Aneurysms.

open access: yesJAMA Netw Open
Meuli L   +8 more
europepmc   +1 more source

Machine learning-based plasma metabolomics for improved cirrhosis risk stratification. [PDF]

open access: yesBMC Gastroenterol
Song J   +10 more
europepmc   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

open access: yesAdvanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua   +19 more
wiley   +1 more source

Validation of the revised 2022 European LeukemiaNet risk stratification in adult patients with acute myeloid leukemia. [PDF]

open access: yesBlood Adv
Ruhnke L   +47 more
europepmc   +1 more source

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