Results 41 to 50 of about 8,596,167 (260)

Relationship Between Psychological Characteristics Mental Health, Aggression and Driving Habits in Dangerous Drivers

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2010
Introduction: Today, all kinds of people need vehicles for performing their daily activities. The need for use of these vehicles for transportation frequently leads to a high rate of road accidents and it seems that certain people do not have enough ...
M Mohammadpoor, I Shakerinia
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Bank Risk-Taking and Monetary Policy: Empirical Results for Taiwan

open access: yes
Will bank risk-taking increase in response to monetary policy easing, especially when interest rates are low, and will banks increase their risk-taking in pursuit of profits?
Kao, Chung-wei;Wan, Jer-yuh
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

ENTREPRENEURIAL CHARACTERISTICS ON ENTREPRENEURIAL TENDENCIES AS AGE MODERATED: A STUDY ON UNIVERSITY INDONESIA [PDF]

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2019
Having the spirit of entrepreneurial is very important for the young generation, seeing the number of unemployed and the lack of land for new workers.
Anggraini V., Rojuaniah, Syah T.Y.R.
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Injuries in Norwegian Early Childhood and Care (ECEC) Institutions

open access: yesNordisk Barnehageforskning, 2017
Children’s play and exploration involves risk and a possibility for being injured. Early childhood and care institutions (ECECs) should provide children with physical challenges in a safe environment. Over the past years, the attention towards playground
Ole Johan Sando   +3 more
doaj   +1 more source

Do Managerial Ability Impact Indonesian Firm Risk-Taking Behavior?

open access: yesAkrual: Jurnal Akuntansi, 2020
This study aims to examine the role of managerial in firm decisions. This study recognizes that managerial plays an important role in corporate decision making.
Emiliya Rahma Wati   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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