Results 121 to 130 of about 6,639,663 (358)

The Effect of Framing on Layoff Decisions: Are More-Experienced Managers More Rational? Does Computerized Data Make Any Difference? [PDF]

open access: yes, 1991
[Excerpt] The effects of framing on decisions has been widely studied, producing research that suggests individuals respond to framing in predictable and fairly consistent ways (Bazerman, 1984, 1990; Tversky & Kahneman, 1986; Thaler, 1980). The essential
Boudreau, John W.
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Local approach to attributable disease burden: a case study on air pollution and mortality in Belgium

open access: yesBMC Public Health
Background Burden of disease estimation and the attribution to risk factors are commonly done on national or regional scale. This research proposes a novel approach, where air pollution-related mortality in Belgium was estimated locally, and compares the
Arno Pauwels   +3 more
doaj   +1 more source

The frequency and risk of metastases in squamous-cell carcinoma of the skin [PDF]

open access: bronze, 1957
Alfred D. Katz   +2 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Search for signals of positive selection of circadian rhythm genes PER1, PER2, PER3 in different human populations

open access: yesВавиловский журнал генетики и селекции
The diversity of geographically distributed human populations shows considerable variation in external and internal traits of individuals. Such differences are largely attributed to genetic adaptation to various environmental influences, which include ...
A. I. Mishina   +10 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

From climate change to cyber-attacks: incipient financial-stability risks for the euro area. Bruegel Policy Contribution Issue n˚2 | February 2020 [PDF]

open access: yes, 2020
The European Central Bank’s November 2019 Financial Stability Review highlighted the risks to growth in an environment of global uncertainty. It also discusses sovereign-debt concerns in case interest rates increase, and risks arising from household and ...
Darvas, Zsolt   +2 more
core  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

The risk rate by ADR road transport of dangerous matters [PDF]

open access: yes, 2009
The paper will be focused on the questions of ADR road transport of dangerous matters, especially on the risks estimation of transport of dangerous goods in the Czech Republic.
Brožová, Pavlína
core   +1 more source

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