Results 181 to 190 of about 2,993,677 (303)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

scientific, social, ecological rationality and public attitudes toward genetically modified food in China: based on the survey of urban residents in three cities of China. [PDF]

GM Crops Food
Li H, Pang Z, Yu T.
europepmc   +1 more source

Ergonomic Risks in the Printing Company and Workers’ Wellbeing

The aim of the study was to analyze the ergonomic risks in the printing company and to study the impact of ergonomics risks on employees’ wellbeing. The study involved 67 company workers aged 18 to 67 years. In the study, physical load evaluation methods
Kaļķis, Valdis, Ieviņš, Jānis, Stradina, Gundega, Roja, Zenija, Kaļķis, Henrijs   +4 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Risking it [PDF]

British Dental Journal, 2000
openaire   +2 more sources

US Patients' Preferences for Geographic Atrophy Treatment. [PDF]

Clin Ophthalmol
Levitan B, Pepio AM, Garg S, Tran N, Krucien N, Csaky K, Aragon M, Irony I, Montague A, Whitty JA, Thomas C.   +10 more
europepmc   +1 more source

Risks Matrixes - Risks Assessment Tools of Small and Medium-Sized Enterprises

The enterprises need to assess the risk dynamic of financial instability and this risk impact on small and medium-sized enterprises’ development, because it is important for enterprises to extend commercial activity and to open a new structural ...
Jansone, Inga, Voronova, Irina
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Nonparametric Assessment of the Calibration of Individualized Treatment Effects. [PDF]

Stat Med
Sadatsafavi M, Hoogland J, Debray TPA, Petkau J.   +3 more
europepmc   +1 more source