Results 221 to 230 of about 7,108,839 (358)

Early age at smoking initiation is associated with elevated cardiovascular disease and mortality risk in a nationwide population-based cohort. [PDF]

Sci Rep
Koh JH, Han K, Kim M, Cho JM, Jung S, Lee S, Kim Y, Cho S, Huh H, Kim SG, Kang E, Joo KW, Kim DK, Park S.   +13 more
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Burden of colorectal cancer attributable to dietary risks in China from 1990 to 2021: findings from the Global Burden of Disease Study 2021. [PDF]

Front Nutr
Chen B, Zheng H, Huang R, Yu J, Wang X, Yang C, Guo Z, Zhan Z.   +7 more
europepmc   +1 more source

Socio-economic status and behavioral risk factor in the adult population. Data from the Italian behavioral surveillance system. Italy, 2010-2012 [PDF]

, 2014
Elisa Quarchioni, Gianluigi Ferrante, Letizia Sampaolo, Lara Bolognesi, Valentina Minardi, Valentina Possenti, Maria Masocco, Nicoletta Bertozzi, Stefano Campostrini, Giuliano Carrozzi, Sandro Baldissera, Angelo D’Argenzio, Pirous Fateh-Moghadam, Maurizio Oddone, Stefania Vasselli, S Salmaso   +15 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

NCI-Designated Cancer Centers' Policies and Practices with regard to Alcohol and Cancer: A Call to Lead. [PDF]

Cancer Epidemiol Biomarkers Prev
Hawk ET, Martch SL, Si M, Shete S.
europepmc   +1 more source

Anti-GD2 Monoclonal Antibody (dinutuximab) with GM-CSF, Interleukin 2, and Cis-retinoic Acid for the Treatment of High-risk Neuroblastoma

, 2016
In Sang Jeon
openalex   +1 more source

1883 The Risk Fields of Malpractice and Strategies for Reducing the risk of Malpractice in Neonatal Nursing [PDF]

, 2012
Dilek Yıldız
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Systemic risk: Opportunities for inter- and transdisciplinary science to improve societal resilience. [PDF]

iScience
Sillmann J, Ciullo A, Franzke CLE, Scheffran J.   +3 more
europepmc   +1 more source