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Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Determinants of proactive health behaviors in individuals at high risks of stroke: a structural equation model analysis. [PDF]

open access: yesFront Public Health
Wang M   +9 more
europepmc   +1 more source
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Risks of Risk Decisions

Science, 1980
The analytical approaches utilized for evaluating the acceptability of technological risk originate from analogies to financial cost-benefit risk analysis. These analogies appear generally valid for viewing risk from a societal basis, but are not applicable to individual risk assessments.
C, Starr, C, Whipple
openaire   +2 more sources

Risk-risk analysis

Journal of Risk and Uncertainty, 1994
Constraints on the use of benefit-cost tests have generated increased interest in risk-risk analysis as a regulatory test. The effect on individual mortality of the income losses arising from regulatory expenditures can be determined from direct empirical estimates, which this article surveys.
openaire   +1 more source

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