Results 71 to 80 of about 7,108,839 (358)

Risks, risk assessment and risk competence in toxicology

German medical science : GMS e-journal, 2015
Das Verständnis der toxischen Wirkungen von Stoffen setzt ein gutes Verständnis der Physiologie bzw. Biochemie voraus. Das häufig beschriebene mangelnde Verständnis in der Bevölkerung für die Pharmakologie und Toxikologie beruht deshalb zu einem großen Teil auf den mangelnden Kenntnissen der erforderlichen Grundlagen.
Stahlmann, R, Horvath, A
openaire   +4 more sources

Computing Individual Risks based on Family History in Genetic Disease in the Presence of Competing Risks [PDF]

, 2017
When considering a genetic disease with variable age at onset (ex: diabetes , familial amyloid neuropathy, cancers, etc.), computing the individual risk of the disease based on family history (FH) is of critical interest both for clinicians and patients.
Bouaziz, O, Lefebvre, Antoine, Nuel, G
core   +3 more sources

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Acceptability of prison-based take-home naloxone programmes among a cohort of incarcerated men with a history of regular injecting drug use

Harm Reduction Journal, 2018
Background Take-home naloxone (THN) programmes are an evidence-based opioid overdose prevention initiative. Elevated opioid overdose risk following prison release means release from custody provides an ideal opportunity for THN initiatives.
Michael Curtis, Paul Dietze, Campbell Aitken, Amy Kirwan, Stuart A. Kinner, Tony Butler, Mark Stoové   +6 more
doaj   +1 more source

Risks to price stability, the zero lower bound and forward guidance: a real-time assessment : [Version August 14, 2013] [PDF]

, 2013
This paper employs stochastic simulations of the New Area-Wide Model—a microfounded open-economy model developed at the ECB—to investigate the consequences of the zero lower bound on nominal interest rates for the evolution of risks to price stability in
Coenen, Günter, Warne, Anders
core  

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Identification and functional characteristic of SARS-CoV-2-specific T lymphocytes in COVID-19 patients up to 16 months after disease onset

Медицинская иммунология
In cases of respiratory viral infection, along with innate immunity mechanisms, the adaptive immune system plays a crucial role in the body’s defence. The efficiency of its cellular component is crucial for pathogen elimination.
I. S. Vladimirov, A. S. Zhdanova, V. E. Mukhin, V. V. Makarov, V. S. Yudin, S. A. Kraevoy   +5 more
doaj   +1 more source

Spatio-temporal dynamics of air temperature and intra-urban thermal disparities in Kasba Tadla (Morocco) during 2023: Implications for local climate adaptation [PDF]

BIO Web of Conferences
Global warming is accelerating significantly, as evidenced by an increase in the frequency, intensity and duration of heat waves. The cities are vulnerable to these extreme thermal phenomena, Due to their morphology and physical characteristics.
Ourabit Souad, Choukri Bahija, Hafid Chaymaa, El Ghachi Mohamed   +3 more
doaj   +1 more source

In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

MethodsX, 2020
Potential health effects of extremely low-frequency (electro)magnetic fields (ELF-(E)MFs) have long been investigated, but the results are still inconclusive. With respect to genotoxicity, sound data related to the effects of long-term exposure to ELF-(E)
Ha Nguyen, Maryse Ledent, Véronique Beauvois, Roel Anthonissen, Luc Verschaeve, Jean-Francois Collard, Maurice Hinsenkamp, Veronique Feipel, Birgit Mertens   +8 more
doaj   +1 more source

Model Risk of Risk Models [PDF]

SSRN Electronic Journal, 2014
This paper evaluates the model risk of models used for forecasting systemic and market risk. Model risk, which is the potential for different models to provide inconsistent outcomes, is shown to be increasing with and caused by market uncertainty. During calm periods, the underlying risk forecast models produce similar risk readings, hence, model risk ...
Danielsson, Jon, James, Kevin R., Valenzuela, Marcela, Zer, Ilknur   +3 more
openaire   +4 more sources