Results 71 to 80 of about 6,639,663 (358)

Study of the protective efficacy of CombiMab-2 against human immunodeficiency virus type 1 in mice humanised with CD4⁺ T-lymphocytes

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Despite existing treatment methods, complete eradication of human immunodeficiency virus (HIV) infection remains an unattainable goal due to the high variability of HIV type 1 (HIV-1).
D. S. Leontyev, F. A. Urusov, D. V. Glazkova, B. V. Belugin, O. V. Orlova, R. R. Mintaev, G. M. Tsyganova, E. V. Bogoslovskaya, G. A. Shipulin   +8 more
doaj   +1 more source

In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

MethodsX, 2020
Potential health effects of extremely low-frequency (electro)magnetic fields (ELF-(E)MFs) have long been investigated, but the results are still inconclusive. With respect to genotoxicity, sound data related to the effects of long-term exposure to ELF-(E)
Ha Nguyen, Maryse Ledent, Véronique Beauvois, Roel Anthonissen, Luc Verschaeve, Jean-Francois Collard, Maurice Hinsenkamp, Veronique Feipel, Birgit Mertens   +8 more
doaj   +1 more source

Model-Based Mitigation of Availability Risks [PDF]

, 2007
The assessment and mitigation of risks related to the availability of the IT infrastructure is becoming increasingly important in modern organizations. Unfortunately, present standards for Risk Assessment and Mitigation show limitations when evaluating ...
Bolzoni, Damiano, Etalle, Sandro, Salvato, Marco, Zambon, Emmanuele   +3 more
core   +7 more sources

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Using actigraphy to assess sleep characteristics

Acta Biomedica Scientifica
Research points to the importance of circadian rhythms for health; their disruptions are associated with various diseases. This has led to the development of circadian medicine, which focuses on using knowledge of physiological rhythms to optimize ...
G. A. Trusov, A. V. Korobeinikova, L. V. Getmantseva, S. Yu. Bakoev, A. N. Lomov, A. A. Keskinov, V. S. Yudin   +6 more
doaj   +1 more source

Failure dynamics of the global risk network [PDF]

, 2015
Risks threatening modern societies form an intricately interconnected network that often underlies crisis situations. Yet, little is known about how risk materializations in distinct domains influence each other.
Asztalos, Andrea, Lin, Xin, Sreenivasan, Sameet, Szymanski, Boleslaw K.   +3 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Acceptability of prison-based take-home naloxone programmes among a cohort of incarcerated men with a history of regular injecting drug use

Harm Reduction Journal, 2018
Background Take-home naloxone (THN) programmes are an evidence-based opioid overdose prevention initiative. Elevated opioid overdose risk following prison release means release from custody provides an ideal opportunity for THN initiatives.
Michael Curtis, Paul Dietze, Campbell Aitken, Amy Kirwan, Stuart A. Kinner, Tony Butler, Mark Stoové   +6 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Lifetime prevalence and correlates of self-harm and suicide attempts among male prisoners with histories of injecting drug use

Health & Justice, 2018
Background Histories of self-harm and suicide attempts are common among people in prison in Australia, and substance dependence is an established risk factor for these lifetime experiences.
Ashleigh C. Stewart, Reece Cossar, Paul Dietze, Gregory Armstrong, Michael Curtis, Stuart A. Kinner, James R. P. Ogloff, Amy Kirwan, Mark Stoové   +8 more
doaj   +1 more source