Results 81 to 90 of about 13,059,962 (346)

Model-Based Mitigation of Availability Risks [PDF]

, 2007
The assessment and mitigation of risks related to the availability of the IT infrastructure is becoming increasingly important in modern organizations. Unfortunately, present standards for Risk Assessment and Mitigation show limitations when evaluating ...
Bolzoni, Damiano, Etalle, Sandro, Salvato, Marco, Zambon, Emmanuele   +3 more
core   +7 more sources

Risks, risk assessment and risk competence in toxicology

German medical science : GMS e-journal, 2015
Das Verständnis der toxischen Wirkungen von Stoffen setzt ein gutes Verständnis der Physiologie bzw. Biochemie voraus. Das häufig beschriebene mangelnde Verständnis in der Bevölkerung für die Pharmakologie und Toxikologie beruht deshalb zu einem großen Teil auf den mangelnden Kenntnissen der erforderlichen Grundlagen.
Stahlmann, R, Horvath, A
openaire   +4 more sources

Cardiovascular Risks Associated with Gender and Aging

Journal of Cardiovascular Development and Disease, 2019
The aging and elderly population are particularly susceptible to cardiovascular disease. Age is an independent risk factor for cardiovascular disease (CVD) in adults, but these risks are compounded by additional factors, including frailty, obesity, and ...
J. L. Rodgers, Jarrod Jones, S. I. Bolleddu, Sahit Vanthenapalli, Lydia E Rodgers, Kinjal Shah, Krishna Karia, S. Panguluri   +7 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Acceptability of prison-based take-home naloxone programmes among a cohort of incarcerated men with a history of regular injecting drug use

Harm Reduction Journal, 2018
Background Take-home naloxone (THN) programmes are an evidence-based opioid overdose prevention initiative. Elevated opioid overdose risk following prison release means release from custody provides an ideal opportunity for THN initiatives.
Michael Curtis, Paul Dietze, Campbell Aitken, Amy Kirwan, Stuart A. Kinner, Tony Butler, Mark Stoové   +6 more
doaj   +1 more source

Multivariate risks and depth-trimmed regions [PDF]

, 2006
We describe a general framework for measuring risks, where the risk measure takes values in an abstract cone. It is shown that this approach naturally includes the classical risk measures and set-valued risk measures and yields a natural definition of ...
C. Acerbi, C. Burgert, E. Jouini, F. Delbaen, G.A. Koshevoy, H. Föllmer, H.J.A.M. Heijmans, I. Cascos, I. Molchanov, Ignacio Cascos, Ilya Molchanov, J.C. Massé, K. Mosler, N. Bäuerle, P. Artzner, P. Embrechts, P.J. Rousseeuw, R. Jarrow, S. Jaschke, W.A.J. Luxemburg, Y. Zuo, Y. Zuo, Y.M. Kabanov   +22 more
core   +7 more sources

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Identification and functional characteristic of SARS-CoV-2-specific T lymphocytes in COVID-19 patients up to 16 months after disease onset

Медицинская иммунология
In cases of respiratory viral infection, along with innate immunity mechanisms, the adaptive immune system plays a crucial role in the body’s defence. The efficiency of its cellular component is crucial for pathogen elimination.
I. S. Vladimirov, A. S. Zhdanova, V. E. Mukhin, V. V. Makarov, V. S. Yudin, S. A. Kraevoy   +5 more
doaj   +1 more source

Spatio-temporal dynamics of air temperature and intra-urban thermal disparities in Kasba Tadla (Morocco) during 2023: Implications for local climate adaptation [PDF]

BIO Web of Conferences
Global warming is accelerating significantly, as evidenced by an increase in the frequency, intensity and duration of heat waves. The cities are vulnerable to these extreme thermal phenomena, Due to their morphology and physical characteristics.
Ourabit Souad, Choukri Bahija, Hafid Chaymaa, El Ghachi Mohamed   +3 more
doaj   +1 more source

Superintelligence as a Cause or Cure for Risks of Astronomical Suffering [PDF]

, 2017
Discussions about the possible consequences of creating superintelligence have included the possibility of existential risk, often understood mainly as the risk of human extinction. We argue that suffering risks (s-risks) , where an adverse outcome would
Gloor, Lukas, Sotala, Kaj
core