Results 101 to 110 of about 4,831,218 (291)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Predicting Sexual Risk Behaviors Related to Human Immunodeficiency Virus Based on the Difficulty of Emotion Regulation in Substance Users

Taḥqīqāt-i ̒Ulūm-i Raftārī, 2018
Aim and Background: In the recent years, the percentage of people diagnosed with acquired immune deficiency syndrome (AIDS) through sexual relations has grown dramatically.
سوده شادکام, جواد ملازاده, عبدالعزیز افلاک سیر   +2 more
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

KOMUNIKASI ORANGTUA-REMAJA DAN PENDIDIKAN ORANGTUA DENGAN PERILAKU SEKSUAL BERISIKO PADA REMAJA

Unnes Journal of Public Health, 2017
Pacaran dan perilaku seksual berkaitan erat satu sama lain. Pacaran akan menghadapkan remaja pada kondisi yang meningkatkan pengalaman seksual. Dilaporkan bahwa perilaku berciuman (48% remaja laki-laki, 30% remaja perempuan), petting (30% remaja laki ...
Erni Gustina
doaj   +1 more source

Risky sexual behavior and associated factors among antiretroviral therapy attendees in Nekemte Referral Hospital, Western Ethiopia: a cross-sectional study

, 2018
Getu Mosisa,1 Kifle Woldemichael,2 Fantahun Ayalew,3,† 1Department of Nursing and Midwifery, College of Health Sciences, Wollega University, Nekemte, Ethiopia; 2Department of Epidemiology, College of Health Sciences, Jimma University, Jimma ...
Mosisa G, Woldemichael K, Ayalew F
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Antiretroviral therapy awareness and risky sexual behaviors : evidence from Mozambique [PDF]

This paper studies the effect of increased access to antiretroviral therapy on risky sexual behavior, using data collected in Mozambique in 2007 and 2008.
Kazianga, Harounan, de Walque, Damien, Over, Mead   +2 more
core  

RISKY SEXUAL BEHAVIOR AMONG IN-SCHOOL YOUTHS: THE INFLUENCE OF PORNOGRAPHY USE AND SOCIO-ENVIRONMENTAL FACTORS ON STUDENTS IN ASSOSA, WESTERN ETHIOPIA

Innovative Issues and Approaches in Social Sciences, 2019
Introduction: This study investigated the influence of pornography use and socio-environmental factors on risky sexual behavior among in-school youths in Assosa, Ethiopia.
Zenaw Alem, Amanti Baru, Nega Jibat
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source