Results 81 to 90 of about 13,094 (300)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Cortisol reactivity to psychosocial stress is greater in sexual risk takers

, 2013
Several studies have reported an association between deviant behaviour and cortisol reactivity to stress. However relatively few studies have investigated the relationship between psychobiological stress reactivity and sexual risk taking behaviours.
Harrison, Claire, Melanie Mitchell, Michael A. Smith, Ratcliffe, Joanne, Mitchell, Melanie, Claire Harrison, Smith, Michael, Joanne M. Ratcliffe   +7 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

An analysis of alcohol use and possible confounding risk factors for risky sexual behaviour amongst women in the rural Western Cape and urban Gauteng provinces

, 2013
Includes abstract.Includes bibliographical references.The general aim of this thesis is therefore to analyse alcohol consumption variables and possible confounding risk factors associated with risky sexual behaviour amongst women in the urban city of ...
Khati, Makobetsa
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Sexual behaviour of grade eleven students in Cofimvaba, Eastern Cape

, 2004
Includes bibliographical references (leaves 67-82).This study deals with sexual behaviour of adolescents in a rural area of South Africa. The primary objective is to explore the sexual behaviour of rural adolescents, specifically with regard to the first
Antwi-Anyimadu, Kofi
core  

'Dark triad' personality traits and risky sexual behaviour [PDF]

, 2013
Thesis (M.A. ( Clinical Psychology)) -- University of Limpopo, 2013This study investigated the relationship between the ‘dark triad’ personality traits and risky sexual behaviour (sociosexuality), and the effect of gender on the relationship ...
Mauda, Lesley Takalani
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Improving the sexual health of women with disabilities in sub-Saharan Africa: a scoping review of published studies

Reproductive Health
Background An essential aspect of human well-being is positive sexual health outcomes. However, the issue of adverse sexual health outcomes continues to be a major public health concern, particularly for women with disabilities in sub-Saharan Africa (SSA)
Obasanjo Afolabi Bolarinwa, Clifford Odimegwu, Talent Tapera   +2 more
doaj   +1 more source

Defining risky sexual behaviour in the UK: a latent class approach

, 2007
This paper aims to define risky sexual behaviour in the UK with respect to the two most common bacterial sexually transmitted diseases: chlamydia and gonorrhoea.
Hinde, Andrew, Sonkin, Beth
core