Results 51 to 60 of about 443,802 (303)

Recurrent individual treatment assignment: a treatment policy approach to account for heterogeneous treatment effects

npj Science of Learning, 2022
Longitudinal randomized controlled trials generally assign individuals randomly to interventions at baseline and then evaluate how differential average treatment effects evolve over time.
Ilja Cornelisz, Chris van Klaveren
doaj   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Rita Bullock

, 1977
Rita Bullock, musical director at Manatee Junior ...

core   +1 more source

Modular Metamaterials for Adaptable MRI Signal Control: Combining Dipole Array With a New Hexagon‐Based Artificial Dielectrics

Advanced Science, EarlyView.
A flexible, hexagonally packed artificial dielectric providing a wide range of effective permittivities (εr ≈ 30–1400) without lumped elements was developed for clinical and ultra‐high‐field MRI. Combined with modular passive‐dipole arrays, the system enables adaptable RF field shaping through electric‐ and magnetic‐dipole tuning.
Santosh Kumar Maurya, Ilan Goldberg, Rita Schmidt   +2 more
wiley   +1 more source

Impact of Acute Functional Decline on Frailty and Mortality in Acutely Hospitalized Older Persons

AGING MEDICINE, EarlyView.
Older persons with acute functional decline are often severely frail. Male sex, cognitive impairment, diabetes mellitus type 2, cancer, hearing impairment, and nursing home living increase the risk of severe frailty or death and should be considered when person‐centered care is planned for hospitalized older people.
Ali Vahedi, Maria Eriksdotter, Hege Ihle‐Hansen, Torgeir Bruun Wyller, Anne Rita Øksengård, Brynjar Fure   +5 more
wiley   +1 more source

Altemeier’s procedure for complete rectal prolapse; outcome and function in 43 consecutive female patients

BMC Surgery, 2019
Background The aim of this retrospective study was to evaluate morbidity, mortality, postoperative function and recurrences in patients treated by Altemeier’s rectosigmoidectomy for complete rectal prolapse in a referral center for pelvic floor ...
Mario Trompetto, Roberta Tutino, Alberto Realis Luc, Eugenio Novelli, Gaetano Gallo, Giuseppe Clerico   +5 more
doaj   +1 more source

Tocilizumab for massive refractory pleural effusion in an adolescent with systemic lupus erythematosus

Pediatric Rheumatology Online Journal, 2021
Background Pleural effusion in systemic lupus erythematous (SLE) is a common symptom, and recent studies demonstrated that IL-6 has a pivotal role in its pathogenesis.
Arianna De Matteis, Emanuela Sacco, Camilla Celani, Andrea Uva, Virginia Messia, Rebecca Nicolai, Manuela Pardeo, Fabrizio De Benedetti, Claudia Bracaglia   +8 more
doaj   +1 more source

Rita Tewari: malaria parasite cell division

Life Science Alliance, 2022
Interview with Rita Tewari Rita Tewari is a Professor of Parasite Cell Biology at The University of Nottingham, Faculty of Medicine and Health Sciences.
Rita Tewari
doaj   +1 more source

Genetic Variation in ADHD‐Related Risk Genes in an Indigenous Population of the Amazon

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Attention‐Deficit/Hyperactivity Disorder (ADHD) is a highly heritable neurodevelopmental disorder; however, its genetic architecture remains poorly explored in Indigenous populations. This study aimed to analyze and characterize genetic variation in 11 genes (ADGRL3, CDH8, DCC, DUSP6, FOXP1, FOXP2, MEF2C, PCDH7, SEMA6D, SORCS3, and ST3GAL3 ...
Hirlesson Paixão de Matos, Natasha Monte, Kaio Evandro Cardoso Aguiar, Rita de Cássia Calderaro, Aline Pasquini Santos, Juliana Carla Gomes Rodrigues, André Maurício Ribeiro‐Dos‐Santos, Sandro José De Souza, Ândrea Ribeiro‐Dos‐Santos, João Farias Guerreiro, Sidney Emanuel Batista Dos Santos, Ney Pereira Carneiro Dos Santos   +11 more
wiley   +1 more source

Involvement of RBP-J interacting and tubulin-associated protein in the distribution of protein regulator of cytokinesis 1 in mitotic spindles

Frontiers in Cell and Developmental Biology
The protein regulator of cytokinesis 1 (PRC1) is a key regulator of microtubule crosslinking and bundling, which is crucial for spindle formation and cytokinesis.
Julia Caspers, Andreas Ritter, Badi Bahrami, Samira Catharina Hoock, Susanne Roth, Alexandra Friemel, Franz Oswald, Frank Louwen, Nina-Naomi Kreis, Juping Yuan   +9 more
doaj   +1 more source