Results 31 to 40 of about 72,871 (224)

Influence of Carrier (Polymer) Type and Drug-Carrier Ratio in the Development of Amorphous Dispersions for Solubility and Permeability Enhancement of Ritonavir

Journal of Excipients and Food Chemicals, 2017
The influence of the ratio of Eudragit® L100-55 or Kolliphor® P188 on the solubility, dissolution, and permeability of ritonavir was studied with a goal of preparing solid dispersions (SDs) of ritonavir.
Vivek S. Dave, Nishikant A. Raut, Deepak Gupta, Suprit D. Saoji, Pradip W. Dhore   +4 more
doaj   +2 more sources

Twice-daily amprenavir 1200 mg versus amprenavir 600 mg/ritonavir 100 mg, in combination with at least 2 other antiretroviral drugs, in HIV-1-infected patients

BMC Infectious Diseases, 2003
Background Low-dose ritonavir (RTV) boosts plasma amprenavir (APV) exposure. Little has been published on the efficacy, tolerability, and safety of APV 600 mg/RTV 100 mg (APV600/RTV) twice daily (BID) compared to APV 1200 mg BID (APV1200).
Griffith Sandy, Liao Qiming, Richmond Gary J, Pollard Richard B, Gathe Joseph C, Nadler Jeffrey P, Tracey Lancaster C, Hernandez Jaime E, Pappa Keith A   +8 more
doaj   +1 more source

A Comparative Study of the Pharmaceutical Properties between Amorphous Drugs Loaded-Mesoporous Silica and Pure Amorphous Drugs Prepared by Solvent Evaporation

Pharmaceuticals, 2022
The formulation of poorly water-soluble drugs is one of the main challenges in the pharmaceutical industry, especially in the development of oral dosage forms.
Arif Budiman, Diah Lia Aulifa
doaj   +1 more source

Changes in insulin sensitivity over time and associated factors in HIV-infected adolescents [PDF]

, 2018
OBJECTIVE: To compare prevalence of insulin resistance between perinatally HIV-infected (PHIV+) and perinatally HIV-exposed, but uninfected adolescents (PHEU), determine incidence of and contributory factors to new and resolved cases of insulin ...
Dimeglio, Linda A., Geffner, Mitchell E., Gerschenson, Mariana, Hazra, Rohan, Jacobson, Denise L., Jao, Jennifer, Miller, Tracie L., Patel, Kunjal, Pediatric HIV/AIDS Cohort Study (PHACS), Sharma, Tanvi, Silio, Margarita, Takemoto, Jody K., Van Dyke, Russell B., Wu, Julia   +13 more
core   +2 more sources

he impact of drug-loading factors on the solid-state form of ritonavir-mesoporous silica systems

British Journal of Pharmacy, 2022
Among the formulation techniques used to enhance the solubility and dissolution rate of poorly, aqueous-soluble drugs, mesoporous silica drug delivery systems have shown promise.
Tanweer Al-Dagamin, Joseph P O'Shea , Abina Crean   +2 more
doaj   +1 more source

Treatment of Young Children with HIV Infection: Using Evidence to Inform Policymakers [PDF]

, 2012
PMCID: PMC3404108This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Abrams, EJ, Cotton, M, Gibb, DM, Mulenga, V, Musoke, P, Penazzato, M, Prendergast, AJ   +6 more
core   +3 more sources

Systemic inflammation and residual viraemia in HIV-positive adults on protease inhibitor monotherapy: a cross-sectional study. [PDF]

, 2015
Increased levels of markers of systemic inflammation have been associated with serious non-AIDS events even in patients on fully suppressive antiretroviral therapy.
Arenas-Pinto, A, Gilson, R, Maini, M, McKendry, A, Milinkovic, A, Peppa, D   +5 more
core   +1 more source

Simultaneous determination of plasma lopinavir and ritonavir by chemometrics-assisted spectrophotometry and comparison with HPLC method [PDF]

Maejo International Journal of Science and Technology, 2013
Chemometrics-assisted spectrophotometry for the determination of two protease inhibitors, lopinavir and ritonavir, in plasma was evaluated. A set of calibration mixtures (calibration set) was designed according to central composite design. The UV spectra
Chutima Matayatsuk Phechkrajang
doaj  

Chemical and Toxicological Analysis of Antiretroviral Drugs

Разработка и регистрация лекарственных средств, 2019
Introduction. Human Immunodeficiency Virus (HIV) is one of the main socially significant infection all over the world. HIV-positive patients take medical care, including antiretroviral drugs (ARVs) pharmacotherapy.
T. N. Komarov, M. V. Belova, D. D. Stolyarova, I. E. Shohin, D. S. Bogdanova, O. A. Miskiv, Yu. V. Medvedev, I. M. Korenskaya   +7 more
doaj   +1 more source

Case Report: Multimodal Imaging of Toxic Retinopathies Related to Human Immunodeficiency Virus Antiretroviral Therapies: Maculopathy vs. Peripheral Retinopathy. Report of Two Cases and Review of the Literature

Frontiers in Neurology, 2021
Purpose: We report two patients with toxic retinopathy from either ritonavir or didanosine and reviewed the literature on the topics. We provide an overview of the retinal toxicity of these two antiretroviral drugs in human immunodeficiency virus ...
Arthur Hammer, François-Xavier Borruat
doaj   +1 more source