Results 81 to 90 of about 53,318 (258)

Stability-indicating method for the determination of Rivaroxaban and its degradation products using LC-MS and TLC [PDF]

, 2018
A validated stability indicating thin layer chromatographic (TLC) and liquid chromatography coupled with mass spectrometry LC/MS methods were developed to analyse Rivaroxaban and its degradation products.
Al-Lahham, Fida, Al-Mardini, Mohammad Amer, Arous, Basima, Ghazal, Heba   +3 more
core   +1 more source

Active Gallbladder Lavage Using a Double‐pigtail Plastic Stent Delivery System During Endoscopic Ultrasound‐guided Gallbladder Drainage (With Video)

DEN Open, Volume 6, Issue 1, April 2026.
Endoscopic ultrasound‐guided gallbladder drainage using a double‐pigtail plastic stent (DPPS) harbors the risk of bile leakage and pneumoperitoneum through the anastomosis site. When the inner sheath of the DPPS system is retracted halfway back into the stent, multiple side holes emerge on the stent end, which accelerates the active gallbladder lavage.
Tesshin Ban, Yoshimasa Kubota, Kei Ando, Naoto Imura, Youta Hirayama, Shun Sasoh, Tomoaki Ando, Takashi Joh   +7 more
wiley   +1 more source

Case report: Severe hepatopathy following rivaroxaban administration in a dog

Frontiers in Veterinary Science
Rivaroxaban, a specific factor Xa inhibitor and commonly utilized anticoagulant, has been known to cause hepatotoxicity and liver failure in humans. Although rivaroxaban is frequently used in veterinary medicine, hepatotoxicity has not been previously ...
Allison P. Mosichuk, Candace Wimbish, Kristen Poplawski, Adam Birkenheuer, Karyn Harrell, Kursten V. Pierce   +5 more
doaj   +1 more source

Characteristics and outcomes in patients with atrial fibrillation receiving direct oral anticoagulants in off-label doses

BMC Cardiovascular Disorders, 2020
Background We evaluated adherence to dosing criteria for patients with atrial fibrillation (AF) taking dabigatran or rivaroxaban and the impact of off-label dosing on thromboembolic and bleeding risk.
Alexandros Briasoulis, Yubo Gao, Chakradhari Inampudi, Paulino Alvarez, Rabea Asleh, Elizabeth Chrischilles, Enrique C. Leira, Mary Vaughan-Sarrazin   +7 more
doaj   +1 more source

High INR on warfarin [PDF]

, 2015
The bottom line Clarify the warfarin dose that the patient is taking, and check for co-existing problems (such as liver disease or cancer), dietary changes, and intake of alcohol and other drugs that may increase risk of bleeding or affect ...
Chevassut, Timothy J, Mallepaddi, Nageswara Rao, Reddy, Udaya   +2 more
core   +1 more source

Safety and Efficacy of Anticoagulation Therapy in Paediatric Patients With Solid Tumours or Lymphomas at Risk of Thrombocytopenia: A Retrospective Study

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo, Katherine Talpin, Bishal Harry, Uma H. Athale, Anthony K. C. Chan, Mihir D. Bhatt   +5 more
wiley   +1 more source

The discovery of rivaroxaban: translating preclinical assessments into clinical practice

Frontiers in Pharmacology, 2013
Direct oral anticoagulants that target a single coagulation factor (such as factor Xa or thrombin) have been developed in recent years in an attempt to address some of the limitations of traditional anticoagulants.
Dagmar eKubitza, Elisabeth ePerzborn, Scott D Berkowitz   +2 more
doaj   +1 more source

NOACs versus warfarin for stroke prevention in patients with AF : a systematic review and meta-analysis [PDF]

, 2016
Acknowledgments Revman software was used for meta-analysis, a free download from the Cochrane Collaboration. GRADE pro software was used to formulate the GRADE summary of findings table, a free download from the GRADE working group.Peer reviewedPublisher
Eisinga, Anne, Hicks, Tim, Stewart, Fiona   +2 more
core   +1 more source

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

Rivaroxaban-induced hemorrhage associated with ABCB1 genetic defect

Frontiers in Pharmacology, 2016
We report a patient who presented a non-ST segment elevation myocardial infarction in the context of severe normocytic hypochromic anemia related to gastrointestinal bleeding, three months after switching anticoagulant from the vitamin K antagonist ...
Kuntheavy Ing Lorenzini, Youssef Daali, Pierre Fontana, Jules Desmeules, Caroline Flora Samer   +4 more
doaj   +1 more source