Results 61 to 70 of about 667,572 (309)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Ice Detection with Sentinel-1 SAR Backscatter Threshold in Long Sections of Temperate Climate Rivers

open access: yesRemote Sensing, 2022
Climate change leads to more variable meteorological conditions. In many Northern Hemisphere temperate regions, cold seasons have become more variable and unpredictable, necessitating frequent river ice observations over long sections of rivers ...
Edvinas Stonevicius   +2 more
doaj   +1 more source

Hydraulics of river ice [PDF]

open access: yesLa Houille Blanche, 1968
La premiere partie du rapport decrit l'ecoulement general a deux phases de grains de materiaux solides flottants, transportes par un ecoulement a surface libre. Nous examinons le mode de transport, par un courant d'eau de densite ρ, de materiaux solides legers de densite ρs ρ, Nous avons pu determiner une analogie complete pour la repartition des ...
openaire   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu   +10 more
wiley   +1 more source

Monitoring Winter Flow Conditions on the Ivishak River, Alaska [PDF]

open access: yes, 2017
The Sagavanirktok River, a braided river on the Alaska North Slope, flows adjacent to the trans-Alaska pipeline for approximately 100 miles south of Prudhoe Bay.
Bailey, J.   +3 more
core  

Episodic warming of near-bottom waters under the Arctic sea ice on the central Laptev Sea shelf [PDF]

open access: yes, 2016
A multiyear mooring record (2007–2014) and satellite imagery highlight the strong temperature variability and unique hydrographic nature of the Laptev Sea.
Benjamin Rabe   +9 more
core   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

open access: yesAdvanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba   +18 more
wiley   +1 more source

Action of River Ice [PDF]

open access: yesNature, 1887
IN the year 1854 the Yellow River burst through its left embankment near Kaifung-fu, and took a new course to the sea through the province of Shantung, occupying in its lower course the bed of the Tatsing-ho, which it scoured out and widened. Prior to the change the Tatsing-ho had been crossed at Tsihohien, about seventeen miles above Tsinan-fu, the ...
openaire   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun   +11 more
wiley   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

open access: yesAdvanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes   +11 more
wiley   +1 more source

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