Results 151 to 160 of about 355,973 (361)

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam   +4 more
wiley   +1 more source

How Do Driving Factors Affect the Ecological Restoration Degree in Different Basins? A Case Study of Six River Basins in Yunnan, China

open access: yesLand
Ecological space provides human beings with the material resources and living environment needed for life; it is the basis for human survival and development, and ecological restoration is directly related to the sustainable development of human society.
Wangxu Qian, Jia Ning
doaj   +1 more source

Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting SPP1‐mediated macrophage polarization via the PI3K/Akt pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang   +10 more
wiley   +1 more source

Full grading detection method of earth-rock materials by combining preliminary screening and video image recognition

open access: yesCase Studies in Construction Materials
Methods for detecting gradation in earth-rock materials using images face challenges, including difficulties in identifying fine-grained stone materials and significant occlusion between different earth-rock components.
Huawei Zhou   +8 more
doaj   +1 more source

Great Bay Estuary Restoration Compendium [PDF]

open access: yes, 2006
Single species approaches to natural resource conservation and management are now viewed as antiquated and oversimplified for dealing with complex systems.
Burdick, David M.   +3 more
core   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Valuing New Hampshire Salt Marshes: An Approach to Measuring Ecosystem Services [PDF]

open access: yes, 2013
David Burdick presented work a method for estimating the ecosystem services benefits of salt marsh restoration. The approach combines ecological valuation, which uses structural and functional indicators to measure the marshes response to restoration ...
Burdick, David M.
core   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt   +4 more
wiley   +1 more source

Re‐evaluation of a soft crested Edmontosaurin, with implications for hadrosaurid life appearance and diversity

open access: yesThe Anatomical Record, EarlyView.
Abstract Hadrosaurid dinosaurs are generally regarded as “crested” or “non‐crested” depending on the presence or absence of a bony cranial crest. At least one supposedly “non‐crested” hadrosaur is known to have possessed a soft tissue cranial crest (or comb), based on an exceptionally preserved “mummified” specimen. Here we redescribe this specimen and
Henry S. Sharpe   +4 more
wiley   +1 more source

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