Results 51 to 60 of about 1,703,409 (309)

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Dynamic evolution trend and driving mechanisms of water conservation in the Yellow River Basin, China

Scientific Reports
Water conservation (WC) is a critical ecological service function in the Yellow River Basin (YRB). There is currently a lack of detailed exploration of WC development processes and the impact mechanisms of driving factors at spatiotemporal scales in the ...
Gaolei Zhao, Shimin Tian, Shuai Liang, Yongcai Jing, Rongxu Chen, Wanwan Wang, Bing Han   +6 more
doaj   +1 more source

The influence of in-stream structures on temperature dynamics via induced hyporheic exchange

Journal of Freshwater Ecology
In-stream restoration structures, such as woody weirs, are intended to enhance hyporheic exchange, thus altering temperature dynamics in restored reaches. However, the relative effects of various in-stream structure types and streambed settings (i.e. the
Jinghong Feng, Junxiong Luo, Ying Liu, Liu Defu, Linlin Li, Ziyan Lu, Xunchuan Song, Weiping Jiang   +7 more
doaj   +1 more source

Determination of restoration potential on small river reaches in urban environment in Hungary

4D, 2023
Urban river reaches are an important element in green infrastructure, but they are typically in worse condition than rural river reaches, so their restoration is an important task.
Tímea Erdei, Zsombor Boromisza, Endre Domokos, Zsófia Földi   +3 more
doaj   +1 more source

From Ambition to Action: Barriers and Enablers for the Inclusion of Indigenous Peoples and Local Communities in the Kunming–Montreal Biodiversity Framework and the Role of Non‐State Bridge Organizations

Advanced Science, EarlyView.
Graphical abstract illustrating the transition from global biodiversity ambition to on‐the‐ground implementation of the Kunming–Montreal Global Biodiversity Framework after COP16, highlighting the roles of governments, non‐state actors, scientific knowledge systems, and resource mobilization in achieving transformative biodiversity outcomes.
Susan Enechojo Ogbe, Jinfeng Zhou, Linda Wong, Jiachen Gao   +3 more
wiley   +1 more source

Coordination analysis of flood-sediment transportation, eco-environment, and socio-economy coupling in the governance of the Yellow River Basin system

Scientific Reports
The watershed system has a complex game relationship between the benign operation and coordinated development of various elements of flood-sediment transportation, eco-environment, and socio-economy (FES).
Gaolei Zhao, Shimin Tian, Enhui Jiang, Yongcai Jing, Rongxu Chen, Xin Wang, Yang Zhang   +6 more
doaj   +1 more source

Comprehensive analysis of heavy metal pollution in the Yellow River Basin from 1980 to 2025: trends, hotspots, and future directions

Frontiers in Ecology and Evolution
Heavy metal pollution poses potential risks to aquatic ecosystems and public health, making it a widespread concern in the Yellow River Basin—one of China’s major energy bases.
Meng Xia, Meng Xia, Meng Xia, Jia Jia, Jia Jia, Jia Jia, Yang Zhang, Yang Zhang, Yang Zhang, Shimin Tian, Shimin Tian, Shimin Tian, Yawei Hu, Yawei Hu, Yawei Hu, Mengzhuo Yang, Mengzhuo Yang, Mengzhuo Yang, Xuejie Zhai, Xuejie Zhai, Xuejie Zhai, Zhanshuo Zhang, Zhanshuo Zhang, Zhanshuo Zhang   +23 more
doaj   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source

IoT-Driven Intelligent Curing of Face Slab Concrete in Rockfill Dams Based on Integrated Multi-Source Monitoring

Buildings
To better understand the temperature changes in face slab concrete and address challenges such as delayed curing and outdated methods in complex and variable environments, this study investigates the use of visualization and real-time feedback control in
Yihong Zhou, Yuanyuan Fang, Zhipeng Liang, Dongfeng Li, Chunju Zhao, Huawei Zhou, Fang Wang, Lei Lei, Rui Wang, Dehang Kong, Tianbai Pei, Luyao Zhou   +11 more
doaj   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source