Results 241 to 250 of about 2,134,823 (333)

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source

Importance and spatial patterns of invisible fisheries in Amazonian clear-water rivers as revealed by fisher knowledge and collaboration. [PDF]

Conserv Biol
Silvano RAM, Vieira KC, Pereyra PER, Tomazoni-Silva LH, Alves IA, Bezerra JG, Dutra MCF, Keppeler FW, Nunes CB, Cunha CV, Hallwass G.   +10 more
europepmc   +1 more source

Particulate organic carbon and nitrogen export from major Arctic rivers

, 2016
James W. McClelland, R. Max Holmes, Bruce J. Peterson, Peter A. Raymond, R. Striegl, A. Zhulidov, S. Zimov, N. Zimov, S. Tank, Robert G. M. Spencer, R. Staples, T. Gurtovaya, C. Griffin   +12 more
semanticscholar   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

Bridging riverine and lacustrine systems: Macroinvertebrate indicators of ecological health in the Rwandan Congo basin. [PDF]

Environ Monit Assess
Ndatimana G, Dusabe MC, Albrecht C.
europepmc   +1 more source

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source

CD4⁺ T cells confer transplantable rejuvenation via Rivers of telomeres

Lanna A, Valvo S, Dustin ML, Rinaldi F.
europepmc   +1 more source

Boreal Rivers as Sources of Terpenoid Emissions. [PDF]

Glob Chang Biol
Hashmi W, Zhang-Turpeinen H, Kohl L, Kuningas A, Palacin-Lizarbe C, Zhu X, Kinnunen N, Marushchak ME, Rinne J, Ojala A, Berninger F, Pumpanen J.   +11 more
europepmc   +1 more source