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Ginsenoside Rk1-Loaded Manganese-Doped Hollow Titania for Enhancing Tumor Sonodynamic Therapy via Upregulation of Intracellular Reactive Oxygen Species.

ACS Applied Materials and Interfaces, 2023
Amplifying the intracellular reactive oxygen species (ROS) level remains an urgent challenge for efficient sonodynamic therapy (SDT) of tumors. Herein, by loading ginsenoside Rk1 with manganese-doped hollow titania (MHT), a Rk1@MHT sonosensitizer was ...
Ming Yang   +9 more
semanticscholar   +1 more source

Ginsenoside Rk1 Prevents UVB Irradiation-Mediated Oxidative Stress, Inflammatory Response, and Collagen Degradation via the PI3K/AKT/NF-κB Pathway In Vitro and In Vivo.

Journal of Agricultural and Food Chemistry, 2022
Long-term exposure to ultraviolet (UV) irradiation, especially UVB, can trigger destructive intracellular effects, including various types of DNA damage, oxidative stress, and inflammatory responses, leading to accelerated skin aging.
Yannan Liu   +4 more
semanticscholar   +1 more source

Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.

Food & Function, 2022
Hepatocellular carcinoma (HCC) is one of the most prevalent and deadly cancers in the world. Recently, suppression of glutamine metabolism has become one of the hottest therapy targets for cancer treatment.
Haoping Lu   +5 more
semanticscholar   +1 more source

Pharmacokinetic studies of ginsenosides Rk1 and Rg5 in rats by UFLC-MS/MS.

Biomedical chromotography, 2021
A rapid ultra-fast liquid chromatography tandem mass spectrometry method was developed and validated to determine ginsenosides Rk1 and Rg5, a pair of isomers, in rat plasma, which was successfully applied to their pharmacokinetic studies.
Chao Ma   +9 more
semanticscholar   +1 more source

KEKERASAN, STRUKTUR MIKRO, DAN CACAT POROSITAS PADA PELEBURAN ALUMINIUM DENGAN VARIASI SUHU 680 C DAN 715 C

JURNAL FOUNDRY, 2022
Produk water cooling magnetron yang berfungsi sebagai pendingin pada elemen panas mengalami kebocoran saat diaplikasikan dengan cara dialirkan cairan pendingin bertekanan tinggi.
Lutiyatmi, Medi Sonianto
semanticscholar   +1 more source

Ginsenoside Rg5/Rk1 ameliorated sleep via regulating the GABAergic/serotoninergic signaling pathway in a rodent model.

Food & Function, 2020
As the most common sleep disorder, insomnia seriously affects people's everyday lives. Phytochemicals have been shown to have excellent sleep-promoting effects.
Jing-Yan Shao   +8 more
semanticscholar   +1 more source

Ginsenoside Rk1 Ameliorates ER Stress-Induced Apoptosis through Directly Activating IGF-1R in Mouse Pancreatic [Formula: see text]-Cells and Diabetic Pancreas.

The American Journal of Chinese Medicine
Hyperglycemia induces chronic stresses, such as oxidative stress and endoplasmic reticulum (ER) stress, which can result in [Formula: see text]-cell dysfunction and development of Type 2 Diabetes Mellitus (T2DM).
C. Vong   +8 more
semanticscholar   +1 more source

The Sun’s distance from the Galactic Centre and mid-plane, and the Galactic old bulge’s morphology: 715 VVV Type II Cepheids

, 2021
A statistical method is employed in tandem with new VISTA Variables in the Via Lactea (VVV) near-infrared observations to determine the Sun’s distance from the Galactic Centre (r0, GC), the Sun’s height from the local mid-plane (z0), and to likewise ...
E. Griv   +4 more
semanticscholar   +1 more source

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