Results 11 to 20 of about 96,834 (121)

A 1.55 R⨁ habitable-zone planet hosted by TOI-715, an M4 star near the ecliptic South Pole [PDF]

Monthly notices of the Royal Astronomical Society, 2023
A new generation of observatories is enabling detailed study of exoplanetary atmospheres and the diversity of alien climates, allowing us to seek evidence for extraterrestrial biological and geological processes.
G. Dransfield, M. Timmermans, A. Triaud, M. Dévora-Pajares, C. Aganze, K. Barkaoui, A. Burgasser, K. Collins, M. Cointepas, E. Ducrot, M. Günther, S. Howell, C. Murray, P. Niraula, B. Rackham, D. Sebastian, K. Stassun, S. Zúñiga-Fernández, J. Almenara, X. Bonfils, F. Bouchy, C. Burke, D. Charbonneau, J. Christiansen, L. Delrez, T. Gan, L. Garcia, M. Gillon, Y. G. M. Chew, K. Hesse, M. Hooton, G. Isopi, E. Jehin, J. Jenkins, D. Latham, F. Mallia, F. Murgas, P. Pedersen, F. Pozuelos, D. Queloz, D. Rodriguez, N. Schanche, S. Seager, G. Srdoc, C. Stockdale, J. Twicken, R. Vanderspek, R. Wells, J. Winn, J. de Wit, Aldo Zapparata   +50 more
semanticscholar   +1 more source

Antiviral Effect of Ginsenosides rk1 against Influenza a Virus Infection by Targeting the Hemagglutinin 1-Mediated Virus Attachment

International Journal of Molecular Sciences, 2023
Influenza A virus (IAV) infections have been a serious hazard to public health everywhere. With the growing concern of drug-resistant IAV strains, there is an urgent need for novel anti-IAV medications, especially those with alternative mechanisms of ...
Xia Yang, Hailiang Sun, Zhening Zhang, Weixin Ou, Fengxiang Xu, Ling Luo, Yahong Liu, Weisan Chen, Jianxin Chen   +8 more
semanticscholar   +1 more source

Ginsenoside Rk1 prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s disease via activating silence information regulator 3-mediated Nrf2/HO-1 signaling pathway

Human and Experimental Toxicology, 2023
Objectives: Ginsenoside Rk1, a novel ginsenoside isolated from red ginseng, has anti-inflammatory and anti-tumor activities. This study was designed to elucidate the role of RK1 in an in vitro 1-methyl-4-phenylpyridinium (MPP+) cell model and an in vivo ...
Yi Ren, Dan Ye, Yiping Ding, Ning Wei
semanticscholar   +1 more source

Identification of Potential Mechanisms of Rk1 Combination with Rg5 in the Treatment of Type II Diabetes Mellitus by Integrating Network Pharmacology and Experimental Validation

International Journal of Molecular Sciences, 2023
In this study, we aimed to explore the potential targets and functional mechanisms of Rk1 combined with Rg5 (Rk1+Rg5) against type II diabetes mellitus (T2DM).
Yao Liu, Jingjing Zhang, Chao An, Chen Liu, Qiwen Zhang, Hao Ding, Sai-jian Ma, Wenjiao Xue   +7 more
semanticscholar   +1 more source

Effect of Soil Temperature on Reproduction of Root-knot Nematodes in Flue-cured Tobacco with Homozygous Rk1 and/or Rk2 Resistance Genes

Journal of nematology, 2023
Most commercial flue-cured tobacco cultivars contain the Rk1 resistance gene, which provides resistance to races 1 and 3 of Meloidogyne incognita and race 1 of M. arenaria. A number of cultivars now possess a second root-knot resistance gene, Rk2.
J. Pollok, Charles S. Johnson, J. Eisenback, T. David, Noah Adamo, R. Sommer   +5 more
semanticscholar   +1 more source

Pharmacokinetics of Ginsenoside Rb1, Rg3, Rk1, Rg5, F2, and Compound K from Red Ginseng Extract in Healthy Korean Volunteers

Evidence-Based Complementary and Alternative Medicine, 2022
Individual differences in ginsenoside pharmacokinetics following ginseng administration in humans are still unclear. We aimed to investigate the pharmacokinetic properties of various ginsenosides, including Rb1, Rg3, Rg5, Rk1, F2, and compound K (CK ...
Hyung-Joong Kim, Tae Kyu Oh, Y. Kim, Jaesun Lee, J. Moon, Y. Park, Chang Min Sung   +6 more
semanticscholar   +1 more source

TAK-715 alleviated IL-1β-induced apoptosis and ECM degradation in nucleus pulposus cells and attenuated intervertebral disc degeneration ex vivo and in vivo

Arthritis Research & Therapy, 2023
Background Intervertebral disc degeneration (IDD) is one of the most common disorders related to the spine. Inflammation, apoptosis and extracellular matrix (ECM) degradation contribute to disc degeneration in nucleus pulposus cells (NPCs).
Kun-Zheng Wang, Dengbo Yao, Yuxi Li, Ming Li, W. Zeng, Zhuangyao Liao, Engming Chen, Shixin Lu, Kaihui Su, Zhen Che, Yuwei Liang, Peng Wang, Lin Huang   +12 more
semanticscholar   +1 more source

Suppression of Lipid Accumulation in the Differentiation of 3T3-L1 Preadipocytes and Human Adipose Stem Cells into Adipocytes by TAK-715, a Specific Inhibitor of p38 MAPK

Life, 2023
Simple Summary p38 MAPK is emerging as a novel regulator in (pre)adipocyte differentiation. TAK-715 is a selective inhibitor of p38 MAPK, but its anti-adipogenic effect and mechanism during the differentiation of preadipocytes and human adipose stem ...
N. Perumal, Amila Mufida, A. Yadav, D. Son, Y. Ryoo, Sung-Ae Kim, B. Jang   +6 more
semanticscholar   +1 more source

Speed thrills but kills: A case study on seasonal variation in roadkill mortality on National highway 715 (new) in Kaziranga-Karbi Anglong Landscape, Assam, India

Natureza & Conservação, 2022
Animal-vehicle collision on the roads is a major cause of mortality of a wide range of animal taxa both within and around protected areas. This study has been conducted in the National Highway 715 (new) covering a continuous stretch of 64 km that passes ...
Somoyita Sur, P. Saikia, M. K. Saikia
semanticscholar   +1 more source

Stock Assessment and Overexploitation Risk of Small Pelagic Fish in Fisheries Management Area 715 of Indonesia

Asian Fisheries Science, 2022
This study presents updated stock assessments and risk analyses of overexploitation for the aggregate small pelagic fish complex and the dominant genus of the complex, Decapterus, for improving the management of the small pelagic fishery in Fisheries ...
P. Purwanto, E. Franklin, Ses Rini Mardiani, Alan T. White   +3 more
semanticscholar   +1 more source