Results 141 to 149 of about 53,462 (149)

Quality of Life in the Phase 2/3 Trial of N-803 Plus Bacillus Calmette-Guérin in Bacillus Calmette-Guérin‒Unresponsive Nonmuscle-Invasive Bladder Cancer

Urology Practice
Introduction: In the phase 2/3 study QUILT-3.032 (NCT03022825), the ability of the IL-15RαFc superagonist N-803 (nogapendekin alfa inbakicept) plus bacillus Calmette-Guérin (BCG) to elicit durable complete responses in patients with BCG-unresponsive ...
K. Chamie, Sam S. Chang, E. Kramolowsky, M. Gonzalgo, Megan Huang, Paul Bhar, Patricia Spilman, Lennie Sender, Sandeep Reddy, P. Soon-Shiong   +9 more
semanticscholar   +1 more source

Lung-MAP S1800D: A phase II/III study of N-803 (ALT-803) plus pembrolizumab versus standard of care in participants with stage IV or recurrent non-small cell lung cancer (NSCLC) previously treated with anti-PD-1 or anti-PD-L1 therapy.

Journal of Clinical Oncology
2619 Background: IL-15 is a member of the IL-2 common gamma chain family of cytokines. N-803 is IL-15 administered in complex with IL-15 receptor alpha.
J. Wrangle, M. Redman, Hatim Husain, K. Reckamp, T. Stinchcombe, Martin J Edelman, Ticiana Leal, B. Faller, K. Minichiello, Hossein Borghaei, Karen Kelly, Roy S. Herbst, J.E. Gray   +12 more
semanticscholar   +1 more source

Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial

Nature Network Boston, 2022
Jeffrey S. Miller, Z. Davis, E. Helgeson, C. Reilly, Ann Thorkelson, Jodi L Anderson, N. Lima, S. Jorstad, G. Hart, John H. Lee, J. Safrit, H. Wong, S. Cooley, Lavina Gharu, Hyunsoo Chung, P. Soon-Shiong, C. Dobrowolski, C. Fletcher, J. Karn, D. Douek, T. Schacker   +20 more
semanticscholar   +1 more source

Investigation of the mixed origins of the MGC-803 cell line reveals that it is a hybrid cell line derived from HeLa.

Human Cell, 2023
Meimei Yang, Jing He, Sixuan Xia, Yudong Wang, Jun Xiong, Cong Liao, Nan Li, Sanfu Qu, Chao Shen   +8 more
semanticscholar   +1 more source

FRA-1 suppresses apoptosis of Helicobacter pylori infected MGC-803 cells

Molecular Biology Reports, 2021
Yang Yang, Benshuai You, Surong Dong, Chenglin Zhou   +3 more
semanticscholar   +1 more source

Effects of Birinapant on Proliferation and Invasion of MGC-803 Gastric Cancer Cells and Mechanism Underlying These Effects

Bulletin of experimental biology and medicine, 2021
D. Zhu, L. Shuai
semanticscholar   +1 more source

Apoptosis of human gastric carcinoma MGC-803 cells induced by a novel Astragalus membranaceus polysaccharide via intrinsic mitochondrial pathways.

International Journal of Biological Macromolecules, 2019
Juan Yu, Haiyu Ji, Xiao-dan Dong, Ying-ying Feng, An-jun Liu   +4 more
semanticscholar   +1 more source

Identification and characterization of a meta-cleavage product hydrolase involved in biphenyl degradation from Arthrobacter sp. YC-RL1

Applied Microbiology and Biotechnology, 2019
Yang Jia, Junhua Wang, Chao Ren, Ruth Nahurira, I. Khokhar, Jiayi Wang, Shuanghu Fan, Yanchun Yan   +7 more
semanticscholar   +1 more source

RADICLELESS 1 (RL1)-mediated nad4 intron 1 splicing is crucial for embryo and endosperm development in rice (Oryza sativa L.).

Biochemical and Biophysical Research Communications - BBRC, 2019
Ming-Wei Wu, Heng Zhao, Jindan Zhang, Lei Guo, Chun-Ming Liu   +4 more
semanticscholar   +1 more source