Results 21 to 30 of about 364,639 (249)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Study on reference material of heavy metals (lead, cadmium, arsenicic, and mercury) in mustard greens by natural infection method

Tạp chí Kiểm nghiệm và An toàn thực phẩm
Vegetables are an essential part of daily meals. Each type contains different nutrients and serves various functions, but all provide essential nutrients for human health.
Tran Hoang Giang, Dinh Viet Chien, Nguyen Minh Chau, Le Van Ha, Lu Thi Minh Hien, Pham Thu Giang, Tran Thi Cham   +6 more
doaj   +1 more source

Thinking green: The role of smart technologies in transforming cities’ waste and supply Chain’s flow

Cleaner Engineering and Technology, 2021
The literature on sustainability is vast and spans across social, economic and environmental domains. This paper looks at the role digital technologies can have in helping the transition to environmentally sustainable conducts across the different ...
Luisa Franchina, Alessandro Calabrese, Giulia Inzerilli, Enrico Scatto, Giulia Brutti, María Victoria de los Ángeles Bonanni   +5 more
doaj   +1 more source

Scintillation properties of $({\rm Zn}_{0.9} {\rm Pb}_{0.1})({\rm W}_{0.9} {\rm Mo}_{0.1}){\rm O}_4$ and $({\rm Zn}_{0.9} {\rm Cd}_{0.1})({\rm W}_{0.9} {\rm Mo}_{0.1}){\rm O}_4$ mixed crystals

, 2020
9 pages, 4 figures, 3 ...
~Galashov, E. N., ~Matvienko, D. V., ~Moskovskyh, V. A., ~Sikach, B. I., ~Shwartz, B. A.   +4 more
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

LESIONES MUSCULARES DEPORTIVAS: DIAGNOSTICO POR IMAGENES

Revista Chilena de Radiología
La gran mayoría de la patología muscular es de origen traumático y relacionado a la actividad deportiva. Alrededor de un 30% de las lesiones en atletas afectan los músculos: En los últimos años ha habido un importante progreso en el diagnóstico de estas ...
Sara Muñoz Ch.
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Machine learning vs. conventional statistical models for predicting heart failure readmission and mortality

ESC Heart Failure, 2021
Aims This study aimed to review the performance of machine learning (ML) methods compared with conventional statistical models (CSMs) for predicting readmission and mortality in patients with heart failure (HF) and to present an approach to formally ...
Sheojung Shin, Peter C. Austin, Heather J. Ross, Husam Abdel‐Qadir, Cassandra Freitas, George Tomlinson, Davide Chicco, Meera Mahendiran, Patrick R. Lawler, Filio Billia, Anthony Gramolini, Slava Epelman, Bo Wang, Douglas S. Lee   +13 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source