Results 231 to 240 of about 2,869,940 (329)

Single-cell RNA sequencing using split-pool barcoding reveals transcriptional heterogeneity in <i>Porphyromonas gingivalis</i> with implications for periodontal pathogenesis. [PDF]

J Oral Microbiol
Jang EY, Yang SB, Chun J, Kwack KH, Kang SW, Lee JH, Moon JH.   +6 more
europepmc   +1 more source

TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes

Journal of Immunology, 2015
T. Eigenbrod, K. Pelka, E. Latz, B. Kreikemeyer, A. Dalpke   +4 more
semanticscholar   +1 more source

NIR Driven Pd/Cerium Oxide Nano‐Heterojunction for Enhanced Salvaging Sepsis Induced Acute Liver Injury via Reprogramming Redox Homeostasis in Synergy with Inducing Autophagy

Advanced Science, EarlyView.
In vivo SALI therapy is achieved by scavenging intracellular ROS levels, downregulating inflammatory factors expression levels, inducing macrophage M2 directional polarization, and activating Keap1/Nrf‐2/HO‐1 pathway to reprogram redox homeostasis, induce cellular autophagy, reduce systemic inflammation, and promote liver tissue repair. Abstract Sepsis
Tao Qin, Lian Qin, Yang Zhao, Yin Chen, Qianyue Liu, Xiaoguang Lin, Yongfeng Lan, Yaohui Huang, Yan Liu, Ke Zhang, Lifan Pan, Jiaxiao Li, Kunpeng Duan, Hao Liang, Mingjing Yin, Guiyang Fan, Lian Liu, Yu Deng, Lin Liao, Danke Su, Ming Gao, Junyu Lu   +21 more
wiley   +1 more source

Presence of group II introns in phage genomes. [PDF]

Nucleic Acids Res
Merk LN, Jones TA, Eddy SR.
europepmc   +1 more source

Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses

Journal of Immunology, 2015
T. Eigenbrod, A. Dalpke
semanticscholar   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Molecular determinants of nucleic acid recognition by an RNA-targeting ADP-ribosyltransferase toxin. [PDF]

J Biol Chem
Lv F, Alexei AG, Colautti J, Bullen NP, Whitney JC.   +4 more
europepmc   +1 more source

A Two‐Protein Chemoreceptor Complex Regulates Oxygen Thresholds in Bacterial Magneto‐Aerotaxis

Advanced Science, EarlyView.
Magnetotactic bacteria align with Earth's magnetic field, helping them migrate toward low‐oxygen environments. This study reveals how Magnetospirillum gryphiswaldense uses a specialized flavin adenine dinucleotide (FAD)‐dependent chemoreceptor, composed of two interacting proteins, for precise navigation in oxygen gradients.
Julian Herz, Carina Weigel, Leonie Scheder, Raz Zarivach, Itay Algov, Yonatan Chemla, Felix Popp, Cornelius Riese, Mohammad A. Charsooghi, Lital Alfonta, Michael M. Meijler, Dirk Schüler, Damien Faivre, Daniel Pfeiffer   +13 more
wiley   +1 more source

The Role of Bacteriophage-Derived Small RNA Molecules in Bacterial and Phage Interactions. [PDF]

Viruses
Lewandowska N, Bloch S, Łukasiak A, Wesołowski W, Węgrzyn G, Nejman-Faleńczyk B.   +5 more
europepmc   +1 more source

Bacterial versatility requires DEAD-box RNA helicases.

FEMS Microbiology Reviews, 2015
Peter Redder, S. Hausmann, Vanessa Khemici, Haleh Yasrebi, P. Linder   +4 more
semanticscholar   +1 more source