Results 151 to 160 of about 123,859 (242)

An extreme type of new onset refractory status epilepticus with stimulus‐induced seizures in pharmacological isoelectric states

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is a common neurological emergency associated with high morbidity and mortality. SE is classified as refractory when it persists despite benzodiazepine and second‐line antiseizure medication. Managing refractory SE in the intensive care setting often requires high doses of sedative drugs, which can induce ...
Julie Lévi‐Strauss, Vi‐Huong Nguyen‐Michel, Espártaco Moraes Ribeiro, Virginie Lambrecq, Aurélie Hanin, Sophie Demeret, Vincent Navarro   +6 more
wiley   +1 more source

Phytomycobiomes and Ecosystem Services: Mechanisms, Evidence and Routes to Application. [PDF]

J Fungi (Basel)
Ansari RA, Egamberdievich KE, Raximovna MT, Sa'dinovna YD, Enverovna BL, Abbasovich AS, Muqumovich AD, Kurbonovich TM.   +7 more
europepmc   +1 more source

Beyond nocardioform: Transcriptionally active microbes and host responses in equine mucoid placentitis

Equine Veterinary Journal, EarlyView.
Abstract Background Nocardioform placentitis (NP) is an understudied form of equine placentitis historically attributed to nocardioform bacteria, yet it remains uncertain whether these organisms are the sole pathogens involved. Objectives To elucidate the pathophysiology of NP and the host–pathogen interaction. Study Design In vivo clinical multi‐omics
Machteld van Heule, Margo Verstraete, Jamie Kaj Norris, Kinga Barbara Graniczkowsa, Kirsten E. Scoggin, Hossam El‐Sheikh Ali, Barry A. Ball, Ward De Spiegelaere, Peter Daels, Bart C. Weimer, Pouya Dini   +10 more
wiley   +1 more source

Clade-wide fungal proteome analysis reveals structure-function conservation in divergent Dicer proteins. [PDF]

Comput Struct Biotechnol J
Melet L, Canan J, Villalobos P, Vidal-Veuthey B, González-Toro F, Orellana I, Rivas-Pardo JA, Cárdenas JP, Moraga C, Castro-Fernández V, Johnson NR, Vidal EA.   +11 more
europepmc   +1 more source

Chronic hepatitis in horses with persistent equine hepacivirus infection

Equine Veterinary Journal, EarlyView.
Abstract Background Equine hepacivirus (EqHV) is closely related to hepatitis C virus (HCV), which causes persistent infection and chronic hepatitis in people. Information on persistent EqHV infection and hepatitis is limited. Objectives To report 19 cases of chronic hepatitis and persistent EqHV infection.
Mason C. Jager, Daniela Luethy, Samantha Shallop, Jessica Cathcart, Thomas J. Divers, Jean‐Yin Tan, Erin McConachie Beasley, Philip Johnson, Laurence Leduc, Claire Smith, Camilla Anne Jamieson, K. Gary Magdesian, Gerlinde R. Van de Walle, Joy E. Tomlinson   +13 more
wiley   +1 more source

Facultative heterochromatin mediated by core and accessory chromosome-encoded H3K27-specific methyltransferases controls virulence in a fungal phytopathogen. [PDF]

Nucleic Acids Res
Janevska S, Gómez-Gil L, Sae-Ong T, Farooq U, Studt-Reinhold L, López-Berges MS, Panagiotou G, Rep M, Di Pietro A.   +8 more
europepmc   +1 more source

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Mycoviruses in Entomopathogenic Fungi. [PDF]

Viruses
Camargo MDS, Edwards S, Henrique MO, Solanki U, Shin TY, Huang B, De Fine Licht HH, Silva-Filho MC, Schrank A, Coutts RHA, Kotta-Loizou I.   +10 more
europepmc   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Overcoming antifungal resistance in <i>Candida albicans via</i> RNA interference: a therapeutic perspective. [PDF]

Front Cell Infect Microbiol
Mundhe AK, Rajkumari R.
europepmc   +1 more source