Results 161 to 170 of about 123,859 (242)

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

The FEBS Journal, EarlyView.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte, Mariana N. R. Trujilho, Karolaine S. S. M. Valdivia, Aline F. Araujo, Laura M. C. de Lorena, Vinicius H. de Oliveira, Beatriz V. Pereira, Emilly R. Leme, Wagner A. S. Júdice, Maurício F. M. Machado   +9 more
wiley   +1 more source

Development of Triangle RNA Nanostructure for Enhancing RNAi-Mediated Control of <i>Botrytis cinerea</i> Through Spray-Induced Gene Silencing Without Extra Nanocarrier. [PDF]

Biology (Basel)
Chen Y, Liu Y, Huang Y, Wu F, Jin W.
europepmc   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

The Viruses of <i>Botrytis cinerea</i> and Beyond: Molecular Characterization of RNA Viruses and Retroplasmids. [PDF]

Viruses
Huang H, Cheng J, Fu Y, Cai Q, Lin Y, Chen T, Li B, Yu X, Xiao X, Jiang D, Xie J.   +10 more
europepmc   +1 more source

Natural‐based antioxidants in cosmeceuticals: Extraction, bioavailability and skin ageing applications

International Journal of Cosmetic Science, EarlyView.
Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian, Arnavaz Akhzarmehr, Charise Dallazem Bertol   +2 more
wiley   +1 more source

RNA editing system: Balancing altruistic antiviral defense and fitness trade-offs in fungi. [PDF]

mLife
Du Y, Jiang D, Liu H.
europepmc   +1 more source

The genome and stage‐specific transcriptomes of the carrot weevil, Listronotus oregonensis, reveal adaptive mechanisms for host specialisation and symbiotic interactions

Insect Molecular Biology, EarlyView.
Comprehensive genome and stage‐specific transcriptomes reveal 14,637 genes in Listronotus oregonensis, advancing genetic insights into a key agricultural pest. Compared with related species, L. oregonensis exhibits reduced chemoreceptor gene families but expanded detoxification gene clusters, reflecting its narrow host range and adaptability.
Dave T. Ste‐Croix, Annie‐Ève Gagnon, Benjamin Mimee   +2 more
wiley   +1 more source

Rice miRNA-mediated trans-kingdom gene regulation in pathogenic and symbiotic fungal interactions. [PDF]

BMC Genomics
Jannesar M, Bassami B, Dalir G, Sheikhzadeh S, Tabrizchi J, Seyedi SM.   +5 more
europepmc   +1 more source

Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF‐κB pathway

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background Inflammation plays an essential role in the pathogenesis of diabetic nephropathy (DN). Linderalactone (LNL), as a natural sesquiterpene lactone, has been discovered to have anti‐inflammatory activation. However, the effects of linderalactone on diabetes‐associated renal damage remain unclear.
Hao Chen, Sheng Xu, Bingrong Chen, Xishan Xiong, Jinrui Hu, Yuhong Wu, Tianrui Wang, Huishang Wang   +7 more
wiley   +1 more source

From Methylomes to CRISPR Epigenetic Editing: New Paths in Antibiotic Resistance. [PDF]

Pathogens
Nass NM, Zaher KA.
europepmc   +1 more source