Results 91 to 100 of about 19,506 (210)

Live‐Cell RNA Imaging via Clickable TriPPPro Nucleotide Reporters

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 2, 9 January 2026.
The intracellular delivery of trans‐cyclooctene and bicyclo[6.1.0]nonyne as sterically demanding groups for the inverse electron‐demand Diels–Alder was achieved by the triphosphate prodrug (TriPPPro) strategy. Once hydrolyzed inside cells, the modified uridines and cytidines are metabolically incorporated into nascent RNA, are labelled by a dual ...
J. Iven H. Knaack   +6 more
wiley   +1 more source

ITSxpress: Software to rapidly trim internally transcribed spacer sequences with quality scores for marker gene analysis [version 1; referees: 2 approved]

open access: yesF1000Research, 2018
The internally transcribed spacer (ITS) region between the small subunit ribosomal RNA gene and large subunit ribosomal RNA gene is a widely used phylogenetic marker for fungi and other taxa.
Adam R. Rivers   +4 more
doaj   +1 more source

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang   +14 more
wiley   +1 more source

The use of PCR-RFLP to genetically distinguish the morphologically close species: Ceriodaphnia dubia Richard, 1894 and Ceriodaphnia silvestrii Daday, 1902 (Crustacea Cladocera)

open access: yesBrazilian Journal of Biology
The cladocerans are important components of planktonic and benthic freshwater and good indicators of the trophic state of water bodies. The morphological taxonomy of many species of Cladocera is considered complex with minor differences separating some ...
MJ. Abreu   +3 more
doaj   +1 more source

Dominant yeasts associated to mango (Mangifera indica) and rose apple (Syzygium malaccense) fruit pulps investigated by culture-based methods [PDF]

open access: yesAnais da Academia Brasileira de Ciências
: The biotechnological potential of yeasts associated to different habitats in Colombia has been poorly studied, especially the yeasts associated with different plant structures.
MAURICIO RAMÍREZ-CASTRILLÓN   +3 more
doaj   +2 more sources

Efficient termination of transcription by RNA polymerase I requires the 5 ' exonuclease Rat1 in yeast [PDF]

open access: yes, 2008
During transcription termination by RNA polymerase II on protein-coding genes, the nuclear 5′ exonuclease Rat1/Xrn2 degrades the nascent transcript downstream from the polyadenylation site and “torpedoes” the polymerase.
El Hage, Aziz   +3 more
core   +3 more sources

Rps19R67∆ mutation creates a model of Diamond–Blackfan anemia and reveals downstream mediators of p53 pathway

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
Abstract Diamond–Blackfan anemia (DBA) is a rare bone marrow failure syndrome accompanied by cardiovascular, skeletal, and urogenital abnormalities. Most of the affected individuals carry mutations in ribosomal proteins, including RPS19, a component of the 40S ribosomal subunit.
Juraj Kokavec   +13 more
wiley   +1 more source

A Reassessment of Phylogenetic Relationships in Class Oligohymenophorea (Protista, Ciliophora) Based on Updated Multigene Data

open access: yesEcology and Evolution
Within the ciliate class Oligohymenophorea, many evolutionary relationships among taxa remain unresolved. This study incorporates 97 new sequences from 30 oligohymenophorean populations, including nuclear small subunit ribosomal (SSU‐rRNA) genes, nuclear
Bailin Li   +7 more
doaj   +1 more source

Detection of Cryptosporidium and Giardia duodenalis in Reptiles in Thailand

open access: yesVeterinary Medicine and Science, Volume 12, Issue 1, January 2026.
ABSTRACT Cryptosporidium spp. and Giardia duodenalis are significant intestinal protozoan parasites affecting humans and animals worldwide. These infections are transmitted through the faecal–oral route, by contaminated water, food or close contact with infected hosts.
Chantira Sutthikornchai   +9 more
wiley   +1 more source

A multidimensional platform for the purification of non-coding RNA species [PDF]

open access: yes, 2013
A renewed interest in non-coding RNA (ncRNA) has led to the discovery of novel RNA species and post-transcriptional ribonucleoside modifications, and an emerging appreciation for the role of ncRNA in RNA epigenetics.
Anderson   +80 more
core   +4 more sources

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