Results 241 to 250 of about 538,895 (285)
Some of the next articles are maybe not open access.
Effect of Spermine on Transfer RNA and Transfer RNA-Ribosome Interactions
1988Translation of genetic message requires a coordianted interplay of more than a hundred kinds of macromolecules. Besides the ribosomes, which are multicomponent ribonucleoprotein particles by their own nature, molecules of transfer RNA, aminoacyl-tRNA synthetases, soluble protein factors and mRNA are involved in the process.
Ivana Weygand-Durasevic +4 more
openaire +3 more sources
A study of transfer RNA methylation
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973Abstract The process of enzymatic methylation was studied with yeast tRNAVal1, using as a source of enzyme the protein fraction precipitated from the 105 000 × g supernatant of both rat liver and hepatoma by 50 % (NH4)2SO4 saturation. Under the conditions chosen, the extent of methylation with the hepatoma enzyme was about 1 mole of methyl ...
T.V. Venkstern +2 more
openaire +4 more sources
Effects of 5-fluorocytidine on mammalian transfer RNA and transfer RNA methyltransferases
Biochemical Pharmacology, 1979Abstract Effects of 5-fluorocytidine on mouse liver tRNA and mouse liver tRNA methyltransferases were investigated. tRNA isolated from drug-treated tissue was shown to contain 5-fluorocytidine and 5 fluorouridine. The amounts of all 5-substituted pyrimidine nucleosides such as 5-methylcytidine, 5-methyluridine, pseudouridine and 5,6-dihydrouridine ...
Kurt Randerath +2 more
openaire +3 more sources
Transfer RNA in RNA Tumor Viruses
1977Publisher Summary This chapter reviews that the presence of the majority of the tRNAs inside an RNA tumor virus remains an enigma. The finding that specific tRNA molecules can serve as primers for DNA synthesis is of fundamental importance in the field of molecular biology.
Beth C. Mullin, Larry C. Waters
openaire +2 more sources
Single Crystals of Transfer RNA from Formylmethionine and Phenylalanine Transfer RNA's
Science, 1968Reproducible conditions have been developed for crystallization of transfer RNA. The conditions may be applicable to many pure transfer RNA species since identical procedures (except for initial transfer RNA concentration) yielded good crystals from both yeast and Escherichia coli transfer RNA.
Paul B. Sigler +6 more
openaire +3 more sources
Structural Studies on Transfer RNA: Crystallization of Formylmethionine and Leucine Transfer RNA's
Science, 1969Improved solvent systems were used to crystallize two different transfer RNA species. These crystals show increased mechanical and thermal stability over crystals obtained previously from a similar system. They have sufficient stability and crystalline order to be used in x-ray crystallographic studies.
H. Ishikura +7 more
openaire +3 more sources
Transfer RNAs and transfer RNA-derived small RNAs in cerebrovascular diseases
Experimental NeurologyThis article explores the important functions of transfer RNA and - transfer RNA derived small RNAs (tsRNAs) in cellular processes and disease pathogenesis, with a particular emphasis on their involvement in cerebrovascular disorders. It discusses the biogenesis and structure of tsRNAs, including types such as tRNA halves and tRNA-derived fragments ...
Jiajie, Yuan +14 more
openaire +2 more sources
Biosynthesis of mammalian transfer RNA. Evidence for regulation by deacylated transfer RNA
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976The rate of tRNA synthesis in cultured Friend leukemia cells has been examined as a function of the variation in polyribosome structure produced by treatment with a variety of inhibitors of protein synthesis. The results indicate, in contrast to the conclusions of Bölcsföldi (Bölcsföldi, G. (1974) Exp.
Thomas A. Hamilton, Michael Litt
openaire +3 more sources
Transfer RNA nucleotidyltransferase
1990Publisher Summary All tRNA molecules contain, at the 3′ terminus, the identical-CCA sequence that is required for their acceptor and transfer functions. In prokaryotic cells, no discrete pattern has emerged. In laboratory strains of Escherichia coli , all tRNA genes sequenced encode the -CCA sequence, and mutant strains devoid of tRNA ...
openaire +3 more sources
The FASEB Journal, 1993
Since its theoretical inception, the tRNA molecule has been identified and many of its functions have been described in terms of its structure. However, the molecular basis for the aminoacylation specificity of tRNA has remained largely unsolved until recently, when substantial progress has disclosed fundamental aspects of this process.
openaire +3 more sources
Since its theoretical inception, the tRNA molecule has been identified and many of its functions have been described in terms of its structure. However, the molecular basis for the aminoacylation specificity of tRNA has remained largely unsolved until recently, when substantial progress has disclosed fundamental aspects of this process.
openaire +3 more sources