Results 361 to 370 of about 5,194,805 (386)

RNA–RNA SELEX

2014
Systematic evolution of ligands by exponential enrichment (SELEX) protocol is a valuable technique to identify RNA aptamers interacting with RNA structural motifs. RNA aptamers are mainly resolved with affinity column chromatography and electrophoretic mobility shift assay (EMSA).
openaire   +3 more sources

RNA–RNA Interaction Prediction and Antisense RNA Target Search

Journal of Computational Biology, 2005
Recent studies demonstrating the existence of special noncoding "antisense" RNAs used in post transcriptional gene regulation have received considerable attention. These RNAs are synthesized naturally to control gene expression in C. elegans, Drosophila, and other organisms; they are known to regulate plasmid copy numbers in E. coli as well. Small RNAs
S. Cenk Sahinalp, Can Alkan, Kaizhong Zhang, Joseph H. Nadeau, Emre Karakoc   +4 more
openaire   +4 more sources

RNA that synthesizes RNA

Trends in Genetics, 2001
The discovery of ribozymes in 1982 boosted a hypothesis in which RNA evolved and carried out biological reactions before proteins developed. Now, researchers have found a ribozyme that can replicate RNA – more evidence for this ‘RNA world’.For such a world to have existed, RNA must have catalyzed its own formation, but no known natural ribozyme can do ...
openaire   +2 more sources

RNA-Dependent RNA Polymerases, Viruses, and RNA Silencing

Science, 2002
Most viruses have RNA genomes that are replicated and transcribed into messenger RNA by viral RNA–dependent RNA polymerases (RdRps), usually in concert with other viral and host factors. Many, if not most, eukaryotes also encode putative RdRps that have been implicated in sequence-specific, RNA-triggered gene silencing.
openaire   +3 more sources

Analysis RNA-seq and Noncoding RNA

2016
RNA-Seq is an approach to transcriptome profiling that uses deep-sequencing technologies to detect and accurately quantify RNA molecules originating from a genome at a given moment in time. In recent years, the advent of RNA-Seq has facilitated genome-wide expression profiling, including the identification of novel and rare transcripts like noncoding ...
A. Arrigoni, V. Ranzani, G. Rossetti, I. Panzeri, S. Abrignani, R. J. P. Bonnal, M. Pagani   +6 more
openaire   +3 more sources

RNA helicases: modulators of RNA structure

Trends in Cell Biology, 1994
RNA molecules play an essential role in many cellular processes, often as components of ribonucleoprotein complexes. Like proteins, RNA molecules adopt sequence-specific secondary and tertiary structures that are essential for function; alteration of these structures therefore provides a means of regulating RNA function.
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Near-optimal probabilistic RNA-seq quantification

Nature Biotechnology, 2016
Nicolas L. Bray, Harold Pimentel, P. Melsted, L. Pachter   +3 more
semanticscholar   +1 more source

Mapping and quantifying mammalian transcriptomes by RNA-Seq

Nature Methods, 2008
A. Mortazavi, B. Williams, Kenneth McCue, Lorian Schaeffer, B. Wold   +4 more
semanticscholar   +1 more source

Inhibition of RNA polymerase by RNA

Journal of Molecular Biology, 1963
Suzanne Bourgeois, François Gros, A. Tissières   +2 more
openaire   +3 more sources

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

Analytical Biochemistry, 1987
P. Chomczyński, N. Sacchi
semanticscholar   +1 more source