Rna decay - Open Access .click

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The Nonsense-Mediated Decay RNA Surveillance Pathway

Annual Review of Biochemistry, 2007
Nonsense-mediated mRNA decay (NMD) is a quality-control mechanism that selectively degrades mRNAs harboring premature termination (nonsense) codons. If translated, these mRNAs can produce truncated proteins with dominant-negative or deleterious gain-of-function activities. In this review, we describe the molecular mechanism of NMD.
Miles F. Wilkinson, J. Saadi Imam, Yao-Fu Chang +2 more
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Chapter 2 RNA Processing and Decay in Bacteriophage T4

2009
Bacteriophage T4 is the archetype of virulent phage. It has evolved very efficient strategies to subvert host functions to its benefit and to impose the expression of its genome. T4 utilizes a combination of host and phage-encoded RNases and factors to degrade its mRNAs in a stage-dependent manner.
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Messenger RNA decay during aging and development

Ageing Research Reviews, 2002
Gene expression is a combination of many processes, including transcription, pre-mRNA processing, nucleocytoplasmic transport of mRNA, translation, mRNA decay, and protein modification and decay. Many changes in the programs of gene expression occur during development, differentiation, and aging.
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RNA decay QTL [PDF]