Results 311 to 320 of about 806,296 (336)

Viral RNA-Dependent RNA Polymerases: A Structural Overview

2018
Most emerging and re-emerging human and animal viral diseases are associated with RNA viruses. All these pathogens, with the exception of retroviruses, encode a specialized enzyme called RNA-dependent RNA polymerase (RdRP), which catalyze phosphodiester-bond formation between ribonucleotides (NTPs) in an RNA template-dependent manner.
Cristina Ferrer-Orta, Diego S. Ferrero, Núria Verdaguer   +2 more
openaire   +2 more sources

Erythromycin dependence and RNA polymerase [PDF]

Biochemical Society Transactions, 1995
Bruce A. Maguire, Donald G. Wild
openaire   +2 more sources

[37] DNA-dependent RNA polymerase

1977
Publisher Summary An essential lysine residue in the active center of the catalytic subunit of DNA-dependent RNA polymerase can be affinity labeled with methylthioinosinedicarboxaldehyde (MMPR-OP). The c-amino group of the lysine forms a Schiff base with an aldehyde group of MMPR-OP, which can be converted to the stable amine by mild reduction with ...
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Isolation and Analysis of Plant RNA-Dependent RNA Polymerases

2012
RNA-dependent RNA polymerases (RDRPs) are encoded by RNA viruses as well as eukaryotic organisms such as plants. The function of these cellular RDRPs has been associated with the synthesis of short interfering RNAs (siRNAs), which are essential regulators of genomic integrity and plant viral defense. The multiple gene copies, and functional diversities,
openaire   +3 more sources

Hepatitis C Virus RNA-Dependent RNA Polymerase (NS5B Polymerase)

2003
The hepatitis C virus (HCV) chronically infects approx 4 million patients in the United States alone, and constitutes a major cause of chronic liver disease and hepatocellular carcinoma (1-3). Current antiviral therapies for chronic hepatitis C remain relatively ineffective and have significant side-effects in many patients.
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Color‐Tunable, Excitation‐Dependent, and Time‐Dependent Afterglows from Pure Organic Amorphous Polymers

Advanced Materials, 2020
Kunyan Sui, Tianwen Zhu, Wang Zhang Yuan
exaly  

Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation

Nature, 2020
Manolis Pasparakis, Laurens Wachsmuth, Snehlata Kumari   +2 more
exaly  

An Assay for RNA-Dependent RNA Polymerase Activity

Cold Spring Harbor Protocols, 2006
Craig E. Cameron, John Gledhill, Luyun Huang   +2 more
openaire   +3 more sources

Time‐Dependent Phosphorescence Colors from Carbon Dots for Advanced Dynamic Information Encryption

Advanced Materials, 2021
Qijun Li, Jing Tan, Songnan Qu
exaly  

Orbital-dependent density functionals: Theory and applications

Reviews of Modern Physics, 2008
Leeor Kronik, Stephan Kümmel
exaly